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Apraclonidine - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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Information about Apraclonidine

Generic Name : Apraclonidine
Pronunciation : a pra KLAH ni deen
Latest prescription information about Apraclonidine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y56.5 | Therapeutic Classification : Antiglaucoma Agents
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Trade Names/Brand Names of Apraclonidine

India : 

International : 

Iopidine
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Why is Apraclonidine Prescribed? (Indications)

This medication is an alpha-2-adrenergic agonist, prescribed for short-term treatment of glaucoma in people who are taking other medications for this condition and still have increased pressure in the eye. It lowers the pressure in the eye by decreasing the amount of fluid produced within the eye. Also could be used in diagnosis of Horner's syndrome.

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When should Apraclonidine not be taken? (Contraindications)

Contraindicated in patients who are taking monoamine oxidase inhibitors (MAO inhibitors), and hypersensitivity.

What is the dosage of Apraclonidine?

One to two drops 0.5% ophthalmic solution should be instilled into the affected eye(s) three times daily.

How should Apraclonidine be taken?

It comes as 0.5% solution and a 1% solution to instill into the affected eyes as directed by your physician.

What are the warnings and precautions for Apraclonidine?

• Caution should be exercised in patients with history of depression, sugar, high blood pressure, stroke, Raynaud's disease, inflammation of the blood vessels, fainting, heart, liver, or kidney disease, who are taking other medications, children, during pregnancy and breastfeeding.

It may cause drowsiness, dizziness, or blurred vision, do not drive a car or operate machinery while taking this medication.

Avoid alcohol consumption.

What are the side effects of Apraclonidine?

   Most Common : Increased blood flow, itching, tearing, discomfort, lid edema, dry mouth, unusual or unpleasant taste in your mouth and foreign body sensation.
   Eye : Blanching, blurred vision, pale eye, eye inflammation, red, swollen, itchy, or teary eyes, itching, discharge from eyes, dry eye, foreign body sensation, lid edema and tearing.
   Central Nervous System : Abnormal coordination, weakness, dizziness, depression, headache, sleeplessness, uneasiness, tingling, nervousness and drowsiness.
   Heart : Abnormal heart rhythm, chest pain, chest heaviness or burning.
   Respiratory : Asthma, nose inflammation, shallow breathing, feeling like you might pass out, difficulty in breathing and dry nose.
   Gastrointestinal : Constipation, nausea and inflammation of pharynx.
   Musculoskeletal : Muscle pain.

What are the other precautions for Apraclonidine?

Avoid excess dosage.

What are the storage conditions for Apraclonidine?

Store it in refrigerator (2 - 27C). Protect from light and avoid freezing.




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