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General Information on Apomorphine

Generic Name : Apomorphine

Pronunciation : a poe mor' feen

Latest prescription information about Apomorphine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y46.7 | Therapeutic Classification : Antiparkinson Agents

Trade Names/Brand Names of Apomorphine

India : 

International : 

Apokyn, Ixense, Spontane, Uprima

Why is Apomorphine Prescribed? (Indications)

This medication is a non-selective dopamine agonist, prescribed for acute, intermittent treatment of hypomobility and loss of control of body movements such as muscle stiffness, slow movements, or trouble moving associated with advanced Parkinson's disease. In some cases this medication is used in the treatment of erectile dysfunction. The medication activates the dopamine receptors in the brain. 

When should Apomorphine not to be taken? (Contraindications)

Hypersensitivity and contraindicated when , co-administration with 5HT3 antagonist class (ondansetron, granisetron, dolasetron, palonosetron, and alosetron).

What is the dosage of Apomorphine?

SC: The recommended initial dose is 0.2ml(2mg), 3times/day.
Test dose is recommended.

How should Apomorphine be taken?

It comes as a solution for injection, to be administered by a healthcare provider subcutaneously.

What are the warnings and precautions for Apomorphine?

Caution should be exercised in patients with history of allergy, who are taking other medications, asthma, eye disease, fainting spells, irregular heartbeat, low blood pressure, mental illness, sleep disorder, stroke or mini-stroke, or other brain problems, sudden uncontrolled movements and falls, or heart, kidney, liver or lung disease, during pregnancy and breastfeeding.

It may cause involuntary movement or worsening of the condition.

It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication and get up slowly from bed.

Should not drink alcohol while you are using apomorphine.

What are the side effects of Apomorphine?

  Most Common: Yawning, involuntary movements, nausea, vomiting, bruising, redness at the injection site region, drowsiness, dizziness, runny nose, hallucinations, swelling, chest pain, increased sweating, flushing and pallor.
  Body as Whole: Weakness and dehydration.
  Central Nervous System: Sleeplessness, headache, depression, anxiety, worsening of Parkinson's disease, confusion and fatigue.
  Musculoskeletal: Muscle/Joint pain, limb pain and back pain, pain spreading to the arm or shoulder.
  Gastrointestinal: Constipation and diarrhea.
  Heart: Congestive heart failure, fast or pounding heart beat, slow heart rate, heavy feeling.
  Respiratory: Difficulty in breathing, cough.
  Genitourinary: Urinary tract infection, penis erection that is painful or lasts 4 hours or longer.

What are the other precautions for Apomorphine?

Avoid alcohol consumption while taking this medication.

What are the storage conditions for Apomorphine?

Store it at room temperature (25C), and in an airtight container. Keep away from children.

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elc016, United States

How can I order Zyprima [2mg]?

pdcure, Canada

If Apomorphine is effective on PD, why is it not being developed in tablet form?

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