Allopurinol - Indications, Dosage, Side Effects and Precautions


Information about Allopurinol

Generic Name : Allopurinol
Up-to-date prescription details regarding Allopurinol are provided here.

Pronunciation : (al oh pure'i nole)

Learn the correct pronunciation of the Allopurinol, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

Therapeutic Classification : Gout Therapy

Trade Names/Brand Names of Allopurinol

India :

International :


Why is Allopurinol Prescribed? (Indications)

Allopurinol is prescribed to treat gouty arthritis and prevent specific kidney stones by reducing high uric acid levels in the blood.

This medication is a xanthine oxidase inhibitor, recommended for treating the increased uric acid levels caused by cancer drugs.

When should Allopurinol not be taken? (Contraindications)


What is the dosage of Allopurinol?

Adult: PO- Gout and Hyperuricaemia- Initial: 100 mg/day, may adjust dose according to response. Max: 800 mg/day.
Prevention of hyperuricaemia associated with chemotherapy treatment or enzyme disorders- 600-800 mg/day, starting 2-3 days before cancer treatment.
IV- Gout and Hyperuricaemia: As Na: 200-400 mg/m2/day. Max: 600 mg/day.

How should Allopurinol be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Allopurinol??

• Caution should be exercised in patients with history of kidney or liver diseases, heart problems, bone marrow problems, high blood pressure, diabetes, who are taking other medication, any allergy, children, during pregnancy and breastfeeding.

• It may cause drowsiness, do not drive a car or operate machinery while taking this medication.

• Monitor kidney and liver function regularly while taking this medication.

What are the side effects of Allopurinol?

Gastrointestinal - Diarrhea, nausea and increased level of liver enzymes.
Metabolic - Acute attacks of gout.
Skin - Rash.

What are the other precautions for Allopurinol?

Avoid excess dosage.
Follow the diet and exercise program as directed by your physician.

What are the storage conditions for Allopurinol?

Store it at controlled room temperature (15° to 25°C) and in an airtight container.

Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.

Allopurinol: Drug Treats Gouty Arthritis, Kidney Stones, and High Uric Acid Levels