Information about Allopurinol
Generic Name : Allopurinol
Pronunciation : (al oh pure'i nole)
Latest prescription information about Allopurinol. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Gout Therapy
Advertisement
Trade Names/Brand Names of Allopurinol
India :
More... International :
Zyloprim
Advertisement
Why is Allopurinol Prescribed? (Indications)
Allopurinol is prescribed to treat gouty arthritis and prevent specific kidney stones by reducing high uric acid levels in the blood.
This medication is a xanthine oxidase inhibitor, recommended for treating the increased uric acid levels caused by cancer drugs.
Advertisement
When should Allopurinol not be taken? (Contraindications)
Hypersensitivity.
What is the dosage of Allopurinol?
Adult: PO- Gout and Hyperuricaemia- Initial: 100 mg/day, may adjust dose according to response. Max: 800 mg/day.
Prevention of hyperuricaemia associated with chemotherapy treatment or enzyme disorders- 600-800 mg/day, starting 2-3 days before cancer treatment.
IV- Gout and Hyperuricaemia: As Na: 200-400 mg/m2/day. Max: 600 mg/day.
How should Allopurinol be taken?
It comes as a tablet to take by mouth, with food.
What are the warnings and precautions for Allopurinol?
• Caution should be exercised in patients with history of kidney or liver diseases, heart problems, bone marrow problems, high blood pressure, diabetes, who are taking other medication, any allergy, children, during pregnancy and breastfeeding.
• It may cause drowsiness, do not drive a car or operate machinery while taking this medication.
• Monitor kidney and liver function regularly while taking this medication.
What are the side effects of Allopurinol?
• Gastrointestinal :
Diarrhea, nausea and increased level of liver enzymes.
• Metabolic :
Acute attacks of gout.
• Skin :
Rash.
What are the other precautions for Allopurinol?
Avoid excess dosage.
Follow the diet and exercise program as directed by your physician.
What are the storage conditions for Allopurinol?
Store it at controlled room temperature (15° to 25°C) and in an airtight container.
Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.
Last Updated : July 2018
I have high uric acid[=7.7]. I have pain below heel in both legs. I have taken Zyloric for 2 months and uric acid is reduced from 9 to 7.7. But no improvement in heel pain. Please guide.