Allopurinol is prescribed to treat gouty arthritis and prevent specific kidney stones by reducing high uric acid levels in the blood.
This medication is a xanthine oxidase inhibitor, recommended for treating the increased uric acid levels caused by cancer drugs.
Adult: PO- Gout and Hyperuricaemia- Initial: 100 mg/day, may adjust dose according to response. Max: 800 mg/day.
Prevention of hyperuricaemia associated with chemotherapy treatment or enzyme disorders- 600-800 mg/day, starting 2-3 days before cancer treatment.
IV- Gout and Hyperuricaemia: As Na: 200-400 mg/m2/day. Max: 600 mg/day.
It comes as a tablet to take by mouth, with food.
• Caution should be exercised in patients with history of kidney or liver diseases, heart problems, bone marrow problems, high blood pressure, diabetes, who are taking other medication, any allergy, children, during pregnancy and breastfeeding.
• It may cause drowsiness, do not drive a car or operate machinery while taking this medication.
• Monitor kidney and liver function regularly while taking this medication.
• Gastrointestinal :
Diarrhea, nausea and increased level of liver enzymes.
• Metabolic : Acute attacks of gout.
• Skin : Rash.
Avoid excess dosage.
Follow the diet and exercise program as directed by your physician.
Store it at controlled room temperature (15° to 25°C) and in an airtight container.
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