Alglucerase injection is as an enzyme replacement therapy in patients diagnosed with type I Gaucher’s disease, a genetic disorder with symptoms and signs of anemia or bleeding tendency, liver disorder, and bone disease.
Adults and children 2 years of age and older.
IV - Initial dosage may be as little as 2.5 units/kg 3 times a week upto 60 units/kg as frequently as once a week or as infrequently as every 4 week.
It comes as a solution for injection to be administered by a healthcare provider into the vein.
• Caution should be exercised in patients with history of prostate cancer, any allergy, children especially less than 10 years old, during pregnancy and breastfeeding.
• Monitor liver function, kidney function, and blood counts regularly while taking this medication.
• Extreme caution needed in children less than 2 years of age.
• Local :
Discomfort, itching, burning, swelling and pus.
• Miscellaneous : Fever, abdominal discomfort, nausea, vomiting, fatigue, weakness, headache, swelling in the extremities and diarrhea.
Avoid excess dosage.
Store it in refrigerator (2 - 8°C).
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