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Alefacept - Indications, Dosage, Side Effects and Precautions

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Information about Alefacept

Generic Name : Alefacept
Up-to-date prescription details regarding Alefacept are provided here.

Pronunciation : ah-LEE-fah-sept

Learn the correct pronunciation of the Alefacept, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y43.4 Therapeutic Classification : Immunosuppressants

Trade Names/Brand Names of Alefacept

International :


Amevive

Why is Alefacept Prescribed? (Indications)

Alefacept is a genetically modified immunosuppressive drug prescribed for treating moderate to severe chronic plaque psoriasis in adult patients who are candidates for phototherapy or systemic therapy.

 It works by stopping the action of certain cells in the body that cause the symptoms of psoriasis.

When should Alefacept not be taken? (Contraindications)

Contraindicated in patients with HIV, and hypersensitivity.

What is the dosage of Alefacept?

The recommended dose is 15 mg given once weekly as an intramuscular injection.

How should Alefacept be taken?

It comes as a solution to be administered by a healthcare provider into the large muscle.

What are the warnings and precautions for Alefacept?

• Caution should be exercised in patients with history of cancer, recurrent infection, who are taking radiation therapy, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

• It should not be used in children.

• Avoid live vaccination while taking this medication.

What are the side effects of Alefacept?

Serious Effects - Malignancy and abnormal decrease in lymphocytes.
Most Common - Dizziness, increased cough, muscle pain, nausea, swelling at the injection site and sore throat.
Miscellaneous - Itching, chills, cough, and accidental injury.

What are the other precautions for Alefacept?

Avoid excess dosage.

What are the storage conditions for Alefacept?

Store it in refrigerator (2-8°C).
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