Alefacept is a genetically modified immunosuppressive drug prescribed for treating moderate to severe chronic plaque psoriasis in adult patients who are candidates for phototherapy or systemic therapy.
It works by stopping the action of certain cells in the body that cause the symptoms of psoriasis.
Contraindicated in patients with HIV, and hypersensitivity.
The recommended dose is 15 mg given once weekly as an intramuscular injection.
It comes as a solution to be administered by a healthcare provider into the large muscle.
• Caution should be exercised in patients with history of cancer, recurrent infection, who are taking radiation therapy, any allergy, who are taking other medications, during pregnancy and breastfeeding.
• It may cause dizziness, do not drive a car or operate machinery while taking this medication.
• It should not be used in children.
• Avoid live vaccination while taking this medication.
• Serious Effects :
Malignancy and abnormal decrease in lymphocytes.
• Most Common : Dizziness, increased cough, muscle pain, nausea, swelling at the injection site and sore throat.
• Miscellaneous : Itching, chills, cough, and accidental injury.
Avoid excess dosage.
Store it in refrigerator (2-8°C).
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