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Adenosine - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team on Nov 25, 2013
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Information about Adenosine

Generic Name : Adenosine
Pronunciation : a-DEN-oh-seen
Latest prescription information about Adenosine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the Indian trade name(s) of the drug and its price list.
ICD Code : Y52.2 | Therapeutic Classification : Antiarrhythmics
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Trade Names/Brand Names of Adenosine

India : 

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Why is Adenosine Prescribed? (Indications)

Adenosine is used as an antiarrhythmic agent prescribed to treat specific conditions of irregular heartbeat and also used while performing a stress test of the heart. 
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When should Adenosine not be taken? (Contraindications)

Contraindicated in patients with second-or third-degree AV block, slow heartbeat, and hypersensitivity.

What is the dosage of Adenosine?

Adult- IV- Initial dose: 6 mg given as a rapid intravenous bolus (administered over a 1-2 second period). Repeat Administration: If first dose does not work, 12 mg should be given as a rapid intravenous bolus. This 12 mg dose may be repeated a second time if required.
Child- Initial dose: Give 0.05 to 0.1 mg/kg as a rapid IV bolus. It may be increased up to 0.05 to 0.1 mg/kg if needed.

How should Adenosine be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Adenosine?

• Caution should be exercised in patients with history of lung or breathing problems, gout, any allergy, who are taking other medications, elderly, during pregnancy and breast-feeding.

• It may cause dizziness or lightheadedness, do not drive a car or operate machinery while taking this medication.

• Avoid drinking large amount of caffeinated beverages.

What are the side effects of Adenosine?

   Heart : Facial flushing, temporary rash on the chest, headache, sweating, palpitations, chest pain and low blood pressure.
   Respiratory : Shortness of breath, chest pressure, fast breathing, coughing and head pressure.
   Central Nervous System : Lightheadedness, dizziness, tingling in arms, numbness, apprehension, blurred vision, burning sensation, heaviness in arms, neck and back pain.
   Gastrointestinal : Nausea, diaphoresis, metallic taste, tightness in throat and pressure in groin.

What are the other precautions for Adenosine?

Monitor electrocardiogram (ECG) regularly while taking this medication.

What are the storage conditions for Adenosine?

Store it at controlled room temperature (15º-30ºC), and in an airtight container.
Last Updated : Jul 2018



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