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Adefovir Dipivoxil - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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Information about Adefovir Dipivoxil

Generic Name : Adefovir Dipivoxil
Pronunciation : a-DEF-oh-vir dye-piv-OX-il
Latest prescription information about Adefovir Dipivoxil. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y41.5 | Therapeutic Classification : Antivirals
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Trade Names/Brand Names of Adefovir Dipivoxil

India : 

International : 

Hepsera
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Why is Adefovir Dipivoxil Prescribed? (Indications)

Adefovir Dipivoxil is an antiviral agent prescribed to treat hepatitis B, a chronic viral infection of the liver in patients 12 years and above.

It works by preventing the virus from spreading and infecting new liver cells. 
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When should Adefovir Dipivoxil not be taken? (Contraindications)

Contraindicated in patients who are taking tenofovir, liver enlargement and hypersensitivity.

What is the dosage of Adefovir Dipivoxil?

Adult- PO -The recommended dose is 10mg/day.

How should Adefovir Dipivoxil be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Adefovir Dipivoxil?

• Caution should be exercised in patients with history of kidney, liver diseases, abnormal liver function tests, liver transplant, HIV infection, obesity, any allergy, who are taking other medications, elderly, during pregnancy and breastfeeding.

It should not be used in children less than 12 years old.

Monitor kidney and liver functions regularly while taking this medication.

If condition worsens stop the medication immediately.

Should not be used concurrently with tenofovir disoproxil fumarate or tenofovir disoproxil fumarate-containing products.

What are the side effects of Adefovir Dipivoxil?

   Most Common : Weakness, headache, abdominal pain, diarrhea, nausea, indigestion, flatulence, increased creatinine, and decrease in blood phosphate level.
   Gastrointestinal : Inflammation of pancreas.
   Muscuskeletal : Muscle pain and softening of bones.
   Genitourinary : Kidney failure and Fanconi syndrome.

What are the other precautions for Adefovir Dipivoxil?

It does not stop the spread of HBV to others; avoid sexual contact, sharing of needles and injection supplies.

What are the storage conditions for Adefovir Dipivoxil?

Store it in room temperature (25C), and in an airtight container.
Last Updated : Jul 2018



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