Abacavir is an antiviral drug that is effective against the HIV-1 virus. It acts on an enzyme of the virus called reverse transcriptase, which plays an important role in its multiplication. Though abacavir reduces viral load and may slow the progression of the disease, it does not cure the HIV infection.
Moderate to severe liver disease
Previous allergic reaction to abacavir
Treatment of HIV-1/AIDS along with other medications. Dose in adults is 600 mg daily, as a single dose or divided into two doses.
It comes as a tablet to take with or without food. It is also available in combination with other anti-HIV drugs.
Caution is advised when used in patients with history of depression or at risk for heart disease
Avoid use with alcohol.
Take along with other anti-HIV drugs and not alone, to prevent resistance.
Continue other precautions to prevent spread of HIV infection.
Monitor and treat the signs of lactic acidosis such as upset stomach, fluctuations in heartbeat,unexplained muscle pain, and difficulty in breathing.
Patient's body fat and cardiac parameters should be measured regularly to avoid heart related illness.
Store at room temperature (20° to 25°C).
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