Pyrazinamide - Drug Information

Generic Name : Pyrazinamide
Pronunciation :

ICD Code : Y41.1 | Therapeutic Classification : Anti- Tuberculosis

Trade Name(s) :

India - Pyzina (1000mg), Pyra (1200mg), P Zide (1000mg), Macrozide (1500mg), Pza Ciba (100ml), Alzide (500mg), Pyrazinamide (500mg) (Unicure), Piraldina (250mg), Montozin (500mg), Pyra (500mg) (Briskon Labs), Pyra (500mg), Zed (750mg), Pyrazinamide (500mg), P Mide (500mg), Rizap (750mg), Pyra (750mg), Pza Ciba DT (250mg), Tibimide (500mg), Pyrazinamide (500mg) (Bini), Cavizide (500mg), Zypyra (500mg), Pyzina Kid (300mg), Rizap (1000mg), Pyrazinamide (500mg) (LOCOST), Pymex (500mg), Pyraz (500mg), PZN (500mg), Piraldina (500mg), Pizamax (500mg), Antizide (500mg)


International - Pyrazinamide.

Why is Pyrazinamide Prescribed? (Indications)

This medication is an anti-tuberculosis agent, prescribed for tuberculosis(TB). It works by killing or preventing the growth of certain bacteria that cause tuberculosis.

When should Pyrazinamide not to be taken? (Contraindications)

Contraindicated in patients with severe liver damage.

What is the dosage of Pyrazinamide ?

PO- The recommended dose is, 15 to 30 mg/kg once daily.

How should Pyrazinamide be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Pyrazinamide ?

* Caution should be exercised in patients with history of liver or kidney disease, diabetes, gout, high uric acid level in the blood, alcoholism, who are taking other medications, during pregnancy and breastfeeding.
* Avoid alcohol consumption while taking this medication.
* Avoid live vaccination during treatment period.

What are the side effects of Pyrazinamide ?

General - Fever, porphyria and painful urination.
Gastrointestinal - Nausea, vomiting and loss of appetite.
Blood - Anemia.
Miscellaneous - Joint or muscle pain, rashes, hives, and itching.

What are the other precautions for Pyrazinamide ?

* Avoid excess dosage.

What are the storage conditions for Pyrazinamide ?

Store in a well-closed container at controlled room temperature (15�C to 30�C).

Schedule H

Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.