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Cladribine - Indications, Dosage, Side Effects and Precautions

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Information about Cladribine

Generic Name : Cladribine
Up-to-date prescription details regarding Cladribine are provided here.

Pronunciation : KLAD-ri-been

Learn the correct pronunciation of the Cladribine, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y43.3 Therapeutic Classification : Chemotherapy

Trade Names/Brand Names of Cladribine

International :


Leustatin

Why is Cladribine Prescribed? (Indications)

This medication is a synthetic anti-cancer agent, prescribed for hairy cell leukemia. It works by stopping the growth of tumor cells.

When should Cladribine not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Cladribine?

IV- The recommended dose is a single course given by continuous infusion for 7 consecutive days at a dose of 0.09 mg/kg/day.

How should Cladribine be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Cladribine?

• Caution should be exercised in patients with history of liver or kidney disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breast-feeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

• It may reduce platelet counts; avoid injury or bruising.

• Avoid contact with people who have infections.

Avoid live attenuated vaccination while using this medication.

What are the side effects of Cladribine?

Most Common - Fatigue, nausea, and injection site reactions.
Body as a Whole - Fever, fatigue, chills, weakness, increased sweating, uneasiness and trunk pain.
Gastrointestinal - Nausea, decreased appetite, vomiting, diarrhea, constipation and abdominal pain.
Blood - Bruising and nose bleed.
Central Nervous System - Headache, dizziness and sleeplessness.
Heart - Fast heart rate and fluid retention.
Respiratory - Abnormal breath sounds, cough, abnormal chest sounds and shortness of breath.
Skin - Rash, itching, pain and redness.
Musculoskeletal - Muscle pain and joint pain.

What are the other precautions for Cladribine?

Avoid excess dosage.

What are the storage conditions for Cladribine?

Store this medication as directed by your physician.
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