Rare skin diseases
Recessive Dystrophic Epidermolysis Bullosa (RDEB) occurrs in 10 out of everyone million people and is a very rare disease. The individuals with this disease fail to produce a single protein required to build a collagen that holds skin together. The slightest touch, scrape or bump results in blisters and sloughing off of the skin. The lining of the mouth, esophagus and intestinal tract are also affected.
Harlequin Ichthyosis - Another rare genetic skin disorder, in which the skin appears as thick as a coat of armor and tends to shed off 7-10 times faster than in normal individuals. The skin is covered with thick scales, which crack, giving it a fish-like appearance. There are hairs on these scales too.