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Geriatry-Related Diseases
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Geriatry-Related Diseases | |
Cancer |
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Growing old brings with it an increased risk of developing cancer. Although the big C attacks both the young and the old, it is primarily considered a disease of the old. Why is this so? Explanations are aplenty but one of the most rational hypotheses is that chromosomal instability, the hall mark of cancer, increases with old age. There is an accumulation of chromosomal aberrations with age; the older a person is, the greater is the exposure to various forms of mutagens and carcinogens which cause the aberrations. The human body is endowed with a vigilance system which tracks down these aberrations and repairs the DNA. However, in ageing individuals, the efficiency of this vigilance system wanes and the individual becomes more prone to develop cancer. Besides, the apoE genes which are linked to ageing and heart disease, is also associated with tobacco-related cancer. Some of the common cancers that develop during old age are colorectal cancer, breast cancer and tobacco- related cancers. The treatment of cancer in the old in aimed to cure in case it is detected early. If cure is not possible, then managing the disease, by controlling the symptoms, is the only option. |
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