Last Updated on Jul 10, 2020

About Chemotherapy

Chemotherapy refers to the use of cytotoxic drugs in cancer treatment.'Chemo' means medicine or 'drug'; 'therapy' means 'treatment'.

Chemotherapeutic agents or drugs are 'magic bullets' that destroy the fast-dividing cancer cells. However these drugs are unable to differentiate between the normal cells and the cancer cells and they destroy the former too, in their war against cancer. This leads to certain side effects.

Chemotherapy is used in over half the patients who are treated with cancer. It is used to treat not only the cancer cells in an organ but also to treat distant sites to which the tumor or cancer might have spread. Hence chemotherapy is a systemic therapy, meaning, it treats the body as a whole.

When Chemotherapy was first put into practice there were many side effects and sometimes they proved to be fatal. Now the practice is much safer with better monitoring and the usage of combination therapy. When an oncologist prescribes a chemotherapy regimen, they give a combination of drugs to treat the cancer. Some of these drugs are administered to treat the dividing cells at various stages. The regimen may also include some supportive drugs to minimize the side effects. To get the best results it is important to follow the regimen and the schedule.

In the earlier days, when popping an aspirin for a headache was also referred to as chemotherapy, the word was used in reference to any drug or medicine employed to treat a disease. The word ‘anti-bacterial chemotherapy’ is used when antibiotics are employed to control a disease. In that sense, syphilis-treating arsenic compounds were the first modern chemotherapeutic agents. This was followed by other antibiotics, like Sulphonamides and Penicillin. In the modern sense it primarily refers to the cytotoxic drugs used in cancer treatment.

Cancerous conditions like Hodgkins lymphoma, non-Hodgkins Lymphoma, certain types of leukemia and testicular tumor are fully cured using these cytotoxic drugs.

Chemotherapy agents have also found use to treat non-cancer conditions like overcoming transplant rejections and to treat autoimmune diseases such as rheumatoid arthritis and multiple sclerosis.

Before starting the chemotherapy one needs to check the performance status of the patient. Performance status is usually a score that tells the physician if the patient is fit to undergo chemotherapy or if the dose of the drugs needs to be reduced.

Chemotherapy - References:

  1. MacDiarmid J.A. et al. (2007)
  2. "Bacterially Derived 400 nm Particles for Encapsulation and Cancer Cell Targeting of Chemotherapeutics" Cancer Cell 11, 431-445, May 2007

Latest Publications and Research on Chemotherapy


Anainesem Monday, April 8, 2013

Sorry butch there was also an other mas called Roberto Aquiles Estévez that thought the use of chemotherapy all over the world...

dorinda Sunday, June 24, 2012

is it safe to have oral sex durning chemo treatments, my wife has treatment every three weeks

mini123 Friday, April 27, 2012

thanks for info

CarolynSue Monday, August 22, 2011

Why wouldnt you use Chemo?

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