According to John R. Lukacs, a professor of anthropology who specializes in dental, skeletal and nutritional issues, the key behind better dental health of men as compared to females is reproduction pressures and rising fertility.
He also said that women suffered a more rapid decline in dental health than did men as humans transitioned from hunter-and-gatherers to farmers and more sedentary pursuits, because of dramatic changes in female-specific hormones.
For the study, Lukacs carried out a comprehensive review of records of the frequencies of dental cavities in both prehistoric and living human populations from research done around the world.
He assessed the frequency of dental caries (cavities) by sex to show that women typically experience poorer dental health than men.
"The role of female-specific factors has been denied by anthropologists, yet they attain considerable importance in the model proposed here, because the adoption of agriculture is associated with increased sedentism and fertility," said Lukacs.
He added: "I argue that the rise of agriculture increased demands on women's reproductive systems, contributing to an increase in fertility that intensified the negative impact of dietary change on women's oral health. The combined impacts of increased fertility, dietary changes and division of labour during the move into agricultural societies contributed to the widespread gender differential observed in dental caries rates today."
In his meta-analysis, he considered both prehistoric anthropological and modern health records and found again and again that increases in cavities go in favour of women in adulthood.
Lukacs' review found that women's higher rates of cavities are influenced by three main changes- female sex hormones, the biochemical composition and flow rate of saliva, food cravings, immune response and aversions during pregnancy.
Noting the findings of his own research in 2006, he said that female sex hormones and associated physiological factors can significantly impact cavity formation. A 1954 animal study found that female estrogens, but not male androgens, were correlated to cavity rates.
He argues for a cumulative effect of estrogens, including fluctuations at puberty and high levels during pregnancy that both promote cavities and dietary changes.
Women produce less saliva than do men, reducing the removal of food residue from the teeth, and that during pregnancies the chemical composition changes, reducing saliva's antimicrobial capacity.
Lukacs indicated that women crave high-energy, sweet foods during the third trimester, as well as an aversion to meat in first trimesters.
He, however, said that they still do not have a clear idea how the factors combine to contribute to higher risk of cavities in women as they age.
The findings of the study are detailed in the latest issue of Current Anthropology.