Negative Memory Storage Affects Depression Symptoms: Study

by Colleen Fleiss on  August 17, 2019 at 9:03 PM Mental Health News
RSS Email Print This Page Comment bookmark
Font : A-A+

Inhibiting negative emotions could be future depression treatment, according to research in mice published in JNeurosci.
Negative Memory Storage Affects Depression Symptoms: Study
Negative Memory Storage Affects Depression Symptoms: Study

Groups of neurons that are activated after an experience are thought to be the physical representation of memory. These so-called engrams in the hippocampus could be involved in depression, which is characterized by impaired recall of positive memories and increased recall of negative memories.

Show Full Article


In a mouse model of depression, Tak Pan Wong and colleagues at Douglas Hospital Research Centre tagged the engrams that formed after mice experienced social stress and examined their social avoidance behavior. Even though all mice experienced the same stressor, only some displayed depression behaviors, indicating a predisposition to developing depression.

Activating the engram cells increased social avoidance behavior while suppressing the cells decreased it, suggesting a role in the cognitive symptoms of depression.

Source: Eurekalert

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

Recommended Reading

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive