Medindia
Advertisement

Memory Loss can be Predicted by Comparing High Blood Pressure in Middle Age Versus Old Age

by Kathy Jones on November 14, 2013 at 8:21 PM
Font : A-A+

 Memory Loss can be Predicted by Comparing High Blood Pressure in Middle Age Versus Old Age

New research indicates that people in middle age who have a high blood pressure measure called pulse pressure are more likely to have biomarkers of Alzheimer's disease in their spinal fluid than those with lower pulse pressure.

The research is published in the November 13, 2013, online issue of NeurologyŪ, the medical journal of the American Academy of Neurology.

Advertisement

Pulse pressure is the systolic pressure, or the top number in a blood pressure reading, minus the diastolic, or the bottom number. Pulse pressure increases with age and is an index of the aging of the vascular system.

The study involved 177 people ages 55 to 100 with no symptoms of Alzheimer's disease. Participants had their pulse pressure taken and lumbar punctures to obtain spinal fluid.
Advertisement

The study found that people who have higher pulse pressure are more likely to have the Alzheimer's biomarkers amyloid beta, or plaques, and p-tau protein, or tangles, in their cerebral spinal fluid than those with lower pulse pressure. For every 10 point rise in pulse pressure, the average level of p-tau protein in the spinal fluid rose by 1.5 picograms per millileter. A picogram is one trillionth of a gram.

"These results suggest that the forces involved in blood circulation may be related to the development of the hallmark Alzheimer's disease signs that cause loss of brain cells," said study author Daniel A. Nation, PhD, of the VA San Diego Healthcare System.

The relationship was found in people age 55 to 70, but not in people age 70 to 100.

"This is consistent with findings indicating that high blood pressure in middle age is a better predictor of later problems with memory and thinking skills and loss of brain cells than high blood pressure in old age," Nation said.



Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
World Alzheimer's Day 2021 - 'Know Dementia, Know Alzheimer's
'Hybrid Immunity' may Help Elude COVID-19 Pandemic
Stroop Effect
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
High Blood Pressure Alzheimers Disease Thalassemia Diet Lifestyle and Heart Disease Diet and High Blood Pressure Stress and the Gender Divide Stroke Quiz on Hypertension Heart Attack- Lifestyle Risks Amnesia 

Recommended Reading
Alzheimers Disease
Alzheimer's disease is a progressive neurodegenerative disease affecting memory and thinking and ......
Brain Exercises to Improve Memory
An active brain can certainly help in improving memory by strengthening the connections between ......
Undetected Nutrient Deficiencies: The Cause of Ill Health
Micronutrient and antioxidant deficiencies are most common and go unnoticed. They are the root ......
Vitamin B12 - An Essential Vitamin
If you feel that the persistent or regular incidences of depression have got nothing to do with ......
Amnesia
Amnesia, is profound memory loss caused by a physical injury inflicted on the brain, by an infection...
Diet and High Blood Pressure
High blood pressure or hypertension is defined as a blood pressure of above 140 mm Hg (systolic) and...
Heart Attack- Lifestyle risks
Heart attack is the death of the heart muscle due to loss of blood supply. Simple guidelines to avoi...
High Blood Pressure
High blood pressure or hypertension is a chronic condition, which usually lasts a lifetime once it i...
Stress and the Gender Divide
Stress has become entwined in the current lifestyle of a young working couple and has resulted in th...
Stroke
Stroke can cause permanent disability and it is important to recognize its early warning signs to st...
Thalassemia
Thalassemia is an inherited blood disorder passed on through parental genes causing the body to prod...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use