- Heart attack is a leading cause of death worldwide
- Currently, there is no drug available that can reduce the cardiac damage
- Vitamin E helps prevent muscle damage in heart attack patients
"One of the most effective anti-oxidant and anti-inflammatory agents is vitamin E and its derivatives," said Professor Karlheinz Peter, the Baker Institute's Deputy Director, Basic and Translational Science and lead author of the study.
"Our treatment regime reflects clinical conditions, where patients could receive their first application of vitamin E in the ambulance or upon their arrival in the emergency department, before reopening and stenting the blocked vessel and the following days in hospital before discharge."
"Our next step is to test an already approved formulation of Vitamin E in patients admitted with a heart attack," said Professor Peter.
"We plan to prove that heart function is preserved using sensitive magnetic resonance imaging. Thereby, we hope to establish an inexpensive and effective therapy for patients with heart attack."
"As there is currently no drug available that can reduce the cardiac damage caused by an overshooting inflammation after reopening of a blocked coronary artery, the potential impact of our finding on cardiovascular health would be significant," said Dr Wallert.
We hereby provide an experimental design which potentially can be translated to human trials without concern surrounding the safety of vitamin E applications.