About Careers MedBlog Contact us

Disinhibition That Limits Weight Loss Associated With Impaired Metabolism in Obese Women

by Bidita Debnath on March 22, 2015 at 9:50 PM
Font : A-A+

Disinhibition That Limits Weight Loss Associated With Impaired Metabolism in Obese Women

Obese females' disinhibition (detrimental to eating and behavioral characteristics) that limits successful weight loss is linked to impaired metabolism, reveals a new research. Lead study author Julia Passyn Dunn of Vanderbilt University School of Medicine in Nashville, Tennessee, said that obese females those who are particularly unlikely to lose weight are also those who need to lose weight the most.

Dunn added that those with an eating/behavioral characteristic that especially limits their weight loss also have the most derangement of their metabolism from their elevated weight.


In people with obesity, a broad range of behavioral and metabolic characteristics influences their ability to lose weight. Disinhibition is an eating characteristic common in obesity that occurs with poor response to weight loss interventions.

Dunn noted that when comparing females with obesity and similar body weight and composition, high disinhibition occurs with more severe insulin resistance and more symptoms of depression.

In patients with type 2 diabetes mellitus, those with increased disinhibition scores have longer disease duration and poorer quality of life compared to patients with lower disinhibition, added Dunn.

The authors suggest that the poorer outcomes in the women with high disinhibition may be due to poorer insulin signaling, and that the mechanism driving the association of detrimental behavioral and metabolic characteristic may lead to future treatments.

Source: ANI


Recommended Reading

Latest Obesity News

Gut Health and Obesity: Role of Bacterial Indicator Species
New study attempts to identify bacterial indicator species of obesity and metabolic syndrome in adult and pediatric patients.
 Natural Peptide May Help Reverse Obesity-Related Diseases
A new therapeutic approach using natural peptides may tackle the root cause of obesity-related conditions by preventing systemic inflammation.
Obesity In Children Likely To Rise Over 9% By 2035 In India
By 2035, worldwide, more than 50 percent of the global population will be living with overweight and obesity, stated report.
Does Obesity Hamper the Economic Progress of India?
World Obesity Day is observed on March 4. The day aims to strive towards achieving a reversal of the global obesity crisis.
Obesity can Raise the Risk of Death More Than Believed
How deadly is obesity? Being obese or overweight for a long period of time may boost the risk of death significantly more than previously believed.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close

Disinhibition That Limits Weight Loss Associated With Impaired Metabolism in Obese Women Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests