About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Antibodies Inhibits HIV Infection

by Sheela Philomena on January 17, 2011 at 9:51 AM
Font : A-A+

Antibodies Inhibits HIV Infection

New findings bring scientists closer to new evidence about broadly reactive neutralizing antibodies, which block HIV infection.

Leo Stamatatos of the Seattle Biomedical Research Institute said the major stumbling block in the development of an effective vaccine against HIV is the inability to elicit, by immunization, broadly reactive neutralizing antibodies (NAbs).

Advertisement

These antibodies bind to the surface of HIV and prevent it from attaching itself to a cell and infecting it. However, a fraction of people infected with HIV develop broadly neutralizing antibodies (bNAbs) capable of preventing cell-infection by diverse HIV isolates, which are the type of antibodies researchers wish to elicit by vaccination.

"We've found that the people who develop broadly-reactive neutralizing antibodies-which are about 30 percent of those infected-tend to have a healthier immune system that differs from others who don't develop those antibodies," explained Stamatatos.
Advertisement

He said these antibodies target only a few regions of HIV, which is good from the standpoint of vaccine development.

In addition, the new findings have shown that these antibodies are generated much sooner than previously thought, in some cases as soon as a year after infection.

"These studies provide a strong rationale to begin teasing out the early immunological signals that allow some individuals, but not others, to mount broadly reactive neutralizing antibody responses," added co-author Galit Alter.

The findings were published in the journal PLoS Pathogens.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Test Your Knowledge on Sugar Intake and Oral Health
Test  Your Knowledge on Heart
Test Your Knowlege on Genes
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Oral Health And AIDS AIDS/HIV AIDS/HIV - Epidemiology AIDS/HIV - Clinical Features AIDS/HIV - Health Education AIDS/HIV - Prevention And Transmission AIDS / HIV - Treatment AIDS/HIV- Lab Tests and Faqs Prostitution: Fresh Stakes in the Oldest Trade Flu 

Most Popular on Medindia

Selfie Addiction Calculator Vent Forte (Theophylline) How to Reduce School Bag Weight - Simple Tips Turmeric Powder - Health Benefits, Uses & Side Effects Nutam (400mg) (Piracetam) Sinopril (2mg) (Lacidipine) The Essence of Yoga Indian Medical Journals Find a Doctor Hearing Loss Calculator
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

Antibodies Inhibits HIV Infection Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests