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Medications and their Potential to Cause Increase 'Joint Pain'


This section presents medications that are known to potentially lead to 'Joint Pain' as a side effect. It's important to note that mild side effects are quite common with medications.
Please be aware that the drugs listed here are individual medications and may be part of a broader combination therapy. This information is meant to be a helpful resource but should not replace professional medical advice. If you're concerned about 'Joint Pain', it's best to consult a healthcare professional.
In addition to 'Joint Pain', other symptoms or signs might better match your side effect. We have listed these below for your convenience. If you find a symptom that more closely resembles your experience, you can use it to identify potential medications that might be the cause.

Drugs with the Side Effect - Joint Pain

Anakinra


Most other Common Side Effects: Injection site reactions such as redness, bruising, swelling, and pain, low white blood cell count, chest infection, worsening of condition, urinary tract infection, headache, nausea, diarrhea, sinusitis, flu like-symptoms, and abdominal pain

Anastrozole


Most other Common Side Effects: Injection site reactions such as redness, bruising, swelling, and pain, low white blood cell count, chest infection, worsening of condition, urinary tract infection, headache, nausea, diarrhea, sinusitis, flu like-symptoms, and abdominal pain

Atorvastatin


Most other Common Side Effects: Nose inflammation, diarrhea, pain in extremity, urinary tract infection, indigestion, nausea, muscle and bone pain, muscle spasms, sleeplessness and throat pain

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Balsalazide


Most other Common Side Effects: Headache, abdominal pain, diarrhea, nausea, vomiting

Bedaquiline


Most other Common Side Effects: Nausea, headache, coughing up of blood and chest pain

Belatacept


Most other Common Side Effects: Nausea, headache, coughing up of blood and chest pain

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Ciclesonide


Most other Common Side Effects: Headache, inflammation of nasopharynx/sinuses, upper respiratory tract infection, nasal congestion, pain in extremity and back pain

Cidofovir


Most other Common Side Effects: Headache, inflammation of nasopharynx/sinuses, upper respiratory tract infection, nasal congestion, pain in extremity and back pain

Enzalutamide


Most other Common Side Effects: Weakness, fatigue, back pain, diarrhea, hot flush, swelling in the extremities, muscle pain, headache, upper respiratory infection, muscle weakness, dizziness, sleeplessness, lower respiratory infection, spinal cord compression, cauda equina syndrome, blood in urine, tingling, anxiety, and high blood pressure

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Eprosartan


Most other Common Side Effects: Weakness, fatigue, back pain, diarrhea, hot flush, swelling in the extremities, muscle pain, headache, upper respiratory infection, muscle weakness, dizziness, sleeplessness, lower respiratory infection, spinal cord compression, cauda equina syndrome, blood in urine, tingling, anxiety, and high blood pressure

Etidronate


Most other Common Side Effects: Stomach pain, nausea, vomiting, bloating, constipation, diarrhea, rash

Ezetimibe


Most other Common Side Effects: upper respiratory tract infection and diarrhea

Fenofibric Acid


Most other Common Side Effects: upper respiratory tract infection and diarrhea

Hylan g-f 20


Most other Common Side Effects: joint stiffness, effusion, swelling, warmth and injection site pain

Icodextrin Peritoneal Dialysis Solution


Most other Common Side Effects: joint stiffness, effusion, swelling, warmth and injection site pain

Icosapent Ethyl


Most other Common Side Effects: joint stiffness, effusion, swelling, warmth and injection site pain

Idelalisib


Most other Common Side Effects: joint stiffness, effusion, swelling, warmth and injection site pain

Idursulfase



Most other Common Side Effects: Irregular heart beat, blood clot in lungs, blue or purple coloration of the skin, respiratory failure, infection, headache, fever, rash, itching, redness, hives and high blood pressure

Iloperidone



Most other Common Side Effects: Irregular heart beat, blood clot in lungs, blue or purple coloration of the skin, respiratory failure, infection, headache, fever, rash, itching, redness, hives and high blood pressure

Immune Globulin Intravenous



Most other Common Side Effects: Irregular heart beat, blood clot in lungs, blue or purple coloration of the skin, respiratory failure, infection, headache, fever, rash, itching, redness, hives and high blood pressure

Incobotulinumtoxina



Most other Common Side Effects: Irregular heart beat, blood clot in lungs, blue or purple coloration of the skin, respiratory failure, infection, headache, fever, rash, itching, redness, hives and high blood pressure

Indacaterol



Most other Common Side Effects: Irregular heart beat, blood clot in lungs, blue or purple coloration of the skin, respiratory failure, infection, headache, fever, rash, itching, redness, hives and high blood pressure

Infliximab



Most other Common Side Effects: Irregular heart beat, blood clot in lungs, blue or purple coloration of the skin, respiratory failure, infection, headache, fever, rash, itching, redness, hives and high blood pressure

Insulin Glulisine



Most other Common Side Effects: Irregular heart beat, blood clot in lungs, blue or purple coloration of the skin, respiratory failure, infection, headache, fever, rash, itching, redness, hives and high blood pressure

Interferon Alfa-N3 -Human Leukocyte derived



Most other Common Side Effects: Irregular heart beat, blood clot in lungs, blue or purple coloration of the skin, respiratory failure, infection, headache, fever, rash, itching, redness, hives and high blood pressure

Interferon Alpha- Two B



Most other Common Side Effects: Irregular heart beat, blood clot in lungs, blue or purple coloration of the skin, respiratory failure, infection, headache, fever, rash, itching, redness, hives and high blood pressure

Interferon Gamma 1B


Most other Common Side Effects: Fever, headache, rash, chills, injection site redness, tenderness, fatigue, diarrhea, vomiting

Iron Dextran


Most other Common Side Effects: Fever, headache, rash, chills, injection site redness, tenderness, fatigue, diarrhea, vomiting

Iron Sucrose


Most other Common Side Effects: Fever, headache, rash, chills, injection site redness, tenderness, fatigue, diarrhea, vomiting

Isosorbide


Most other Common Side Effects: Fever, headache, rash, chills, injection site redness, tenderness, fatigue, diarrhea, vomiting

Isotretinoin


Most other Common Side Effects: Fever, headache, rash, chills, injection site redness, tenderness, fatigue, diarrhea, vomiting

Lamivudine


Most other Common Side Effects: Fever, headache, rash, chills, injection site redness, tenderness, fatigue, diarrhea, vomiting

Lamivudine- Zidovudine


Most other Common Side Effects: Fever, headache, rash, chills, injection site redness, tenderness, fatigue, diarrhea, vomiting

Lanreotide


Most other Common Side Effects: Fever, headache, rash, chills, injection site redness, tenderness, fatigue, diarrhea, vomiting

Larotrectinib


Most other Common Side Effects: Fever, headache, rash, chills, injection site redness, tenderness, fatigue, diarrhea, vomiting

Letrozole


Most other Common Side Effects: Fever, headache, rash, chills, injection site redness, tenderness, fatigue, diarrhea, vomiting

Nalmefene



Most other Common Side Effects: Nausea, dizziness, fever, headache, fast heart rate, high blood pressure, chills, muscle aches

Naproxen and Esomeprazole Magnesium



Most other Common Side Effects: Nausea, dizziness, fever, headache, fast heart rate, high blood pressure, chills, muscle aches

Naratriptan



Most other Common Side Effects: Nausea, dizziness, fever, headache, fast heart rate, high blood pressure, chills, muscle aches

Natalizumab


Most other Common Side Effects: Headache, fatigue, urinary tract infection, lower respiratory tract infection, stomach inflammation, vaginal inflammation, depression, pain in extremity, abdominal discomfort, diarrhea, and rash

Nebivolol


Most other Common Side Effects: Headache, fatigue, urinary tract infection, lower respiratory tract infection, stomach inflammation, vaginal inflammation, depression, pain in extremity, abdominal discomfort, diarrhea, and rash

Nilotinib


Most other Common Side Effects: Rash, itching, headache, nausea, fatigue, muscle pain, upper abdominal pain, hair loss, constipation, diarrhea, dry skin, muscle spasms

Nisoldipine


Most other Common Side Effects: Rash, itching, headache, nausea, fatigue, muscle pain, upper abdominal pain, hair loss, constipation, diarrhea, dry skin, muscle spasms

Nitrendipine


Most other Common Side Effects: Rash, itching, headache, nausea, fatigue, muscle pain, upper abdominal pain, hair loss, constipation, diarrhea, dry skin, muscle spasms

Nizatidine


Most other Common Side Effects: Rash, itching, headache, nausea, fatigue, muscle pain, upper abdominal pain, hair loss, constipation, diarrhea, dry skin, muscle spasms

Obinutuzumab


Most other Common Side Effects: Rash, itching, headache, nausea, fatigue, muscle pain, upper abdominal pain, hair loss, constipation, diarrhea, dry skin, muscle spasms

Olanzapine and Fluoxetine


Most other Common Side Effects: Rash, itching, headache, nausea, fatigue, muscle pain, upper abdominal pain, hair loss, constipation, diarrhea, dry skin, muscle spasms

Olaparib


Most other Common Side Effects: Rash, itching, headache, nausea, fatigue, muscle pain, upper abdominal pain, hair loss, constipation, diarrhea, dry skin, muscle spasms

Olmesartan


Most other Common Side Effects: Rash, itching, headache, nausea, fatigue, muscle pain, upper abdominal pain, hair loss, constipation, diarrhea, dry skin, muscle spasms

Olsalazine


Most other Common Side Effects: Rash, itching, headache, nausea, fatigue, muscle pain, upper abdominal pain, hair loss, constipation, diarrhea, dry skin, muscle spasms

Omacetaxine Mepesuccinate


Most other Common Side Effects: Rash, itching, headache, nausea, fatigue, muscle pain, upper abdominal pain, hair loss, constipation, diarrhea, dry skin, muscle spasms

Omeprazole


Most other Common Side Effects: Rash, itching, headache, nausea, fatigue, muscle pain, upper abdominal pain, hair loss, constipation, diarrhea, dry skin, muscle spasms

Paclitaxel


Most other Common Side Effects: Rash, itching, headache, nausea, fatigue, muscle pain, upper abdominal pain, hair loss, constipation, diarrhea, dry skin, muscle spasms

Palifermin


Most other Common Side Effects: Rash, itching, headache, nausea, fatigue, muscle pain, upper abdominal pain, hair loss, constipation, diarrhea, dry skin, muscle spasms

Plerixafor Injection


Most other Common Side Effects: Diarrhea, nausea, fatigue, injection site reactions, headache, dizziness, and vomiting

Pneumococcal Vaccine Polyvalent


Most other Common Side Effects: Diarrhea, nausea, fatigue, injection site reactions, headache, dizziness, and vomiting

Policosanol


Most other Common Side Effects: Diarrhea, nausea, fatigue, injection site reactions, headache, dizziness, and vomiting

Ponatinib


Most other Common Side Effects: High blood pressure, rash, abdominal pain, fatigue, headache, dry skin, constipation, nausea and fever

Potassium- Sodium Phosphate


Most other Common Side Effects: Nausea, vomiting, diarrhea, dizziness, headache, stomach upset, muscle cramps

Pralsetinib


Most other Common Side Effects: Nausea, vomiting, diarrhea, dizziness, headache, stomach upset, muscle cramps

Pramlintide Acetate Injection


Most other Common Side Effects: Nausea, vomiting, diarrhea, dizziness, headache, stomach upset, muscle cramps

Rifapentine



Most other Common Side Effects: Blood in urine, loss of appetite, back pain, and muscle pain

Rifaximin



Most other Common Side Effects: Blood in urine, loss of appetite, back pain, and muscle pain

Risedronate


Most other Common Side Effects: Back pain, abdominal pain, and stomach upset, rash, nausea

Romiplostim


Most other Common Side Effects: Back pain, abdominal pain, and stomach upset, rash, nausea

Rosiglitazone and Metformin


Most other Common Side Effects: Upper respiratory tract infection, diarrhea, injury, anemia, headache, sinusitis, fatigue, back pain, viral infection

Salmeterol


Most other Common Side Effects: Upper respiratory tract infection, diarrhea, injury, anemia, headache, sinusitis, fatigue, back pain, viral infection

Sirolimus


Most other Common Side Effects: Swelling in the extremities, high blood pressure, increased cholesterol level, constipation, abdominal pain, diarrhea, headache, fever, urinary tract infection, anemia, nausea, and decrease in platelet counts

Sitagliptin


Most other Common Side Effects: Swelling in the extremities, high blood pressure, increased cholesterol level, constipation, abdominal pain, diarrhea, headache, fever, urinary tract infection, anemia, nausea, and decrease in platelet counts

Sunitinib


Most other Common Side Effects: Fatigue, weakness, fever, diarrhea, nausea, mouth ulcer, vomiting, indigestion, abdominal pain, constipation, high blood pressure, swelling in the extremities, rash, hand-foot syndrome, skin discoloration, dry skin, hair color changes, altered taste, headache, back pain, cough, difficulty in breathing, loss of appetite, and bleeding

Tadalafil


Most other Common Side Effects: Fatigue, weakness, fever, diarrhea, nausea, mouth ulcer, vomiting, indigestion, abdominal pain, constipation, high blood pressure, swelling in the extremities, rash, hand-foot syndrome, skin discoloration, dry skin, hair color changes, altered taste, headache, back pain, cough, difficulty in breathing, loss of appetite, and bleeding

Taliglucerase Alfa


Most other Common Side Effects: Fatigue, weakness, fever, diarrhea, nausea, mouth ulcer, vomiting, indigestion, abdominal pain, constipation, high blood pressure, swelling in the extremities, rash, hand-foot syndrome, skin discoloration, dry skin, hair color changes, altered taste, headache, back pain, cough, difficulty in breathing, loss of appetite, and bleeding

Tapentadol


Most other Common Side Effects: Fatigue, weakness, fever, diarrhea, nausea, mouth ulcer, vomiting, indigestion, abdominal pain, constipation, high blood pressure, swelling in the extremities, rash, hand-foot syndrome, skin discoloration, dry skin, hair color changes, altered taste, headache, back pain, cough, difficulty in breathing, loss of appetite, and bleeding

Technetium Tc99m Medronate Injection


Most other Common Side Effects: Fatigue, weakness, fever, diarrhea, nausea, mouth ulcer, vomiting, indigestion, abdominal pain, constipation, high blood pressure, swelling in the extremities, rash, hand-foot syndrome, skin discoloration, dry skin, hair color changes, altered taste, headache, back pain, cough, difficulty in breathing, loss of appetite, and bleeding

Telbivudine


Most other Common Side Effects: Fatigue, weakness, fever, diarrhea, nausea, mouth ulcer, vomiting, indigestion, abdominal pain, constipation, high blood pressure, swelling in the extremities, rash, hand-foot syndrome, skin discoloration, dry skin, hair color changes, altered taste, headache, back pain, cough, difficulty in breathing, loss of appetite, and bleeding

Vemurafenib Tablet


Most other Common Side Effects: rash, hair loss, fatigue, photosensitivity reaction, nausea, itching, and skin papilloma

Venlafaxine


Most other Common Side Effects: rash, hair loss, fatigue, photosensitivity reaction, nausea, itching, and skin papilloma

Zoledronic Acid


Most other Common Side Effects: Fever, muscle pain, headache, pain in extremity

Zoster Vaccine Live


Most other Common Side Effects: Fever, muscle pain, headache, pain in extremity

References

  1. https://www.fda.gov/drugs/information-consumers-and-patients-drugs/finding-and-learning-about-side-effects-adverse-reactions
  2. https://nctr-crs.fda.gov/fdalabel/ui/search
  3. https://dailymed.nlm.nih.gov/dailymed/
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