How to Take Dabigatran and Dose of Dabigatran

Written & Compiled by Madhumathi Palaniappan | Medically Reviewed by The Medindia Medical Review Team on Feb 16, 2011

Find out how to take Dabigatran (drug) and its dose. Describes the best time to take the drug and precautions if any that should be followed.

How to take Dabigatran

How it should be taken

It comes as a capsule to take by mouth, with or without food.

Dosage & When it is to be taken

For patients with creatinine clearance (CrCl) > 30 mL/min- The recommended dose is 150 mg taken orally, twice daily.
For patients with CrCl 15-30 mL/min- The recommended dose is 75 mg twice daily.

When it is not to be taken (Contraindications)

Contraindicated in patients with active bleeding and hypersensitivity.

Why it is prescribed (Indications)

This medication is an anticoagulant (thrombin inhibitor), prescribed for preventing strokes or serious blood clots in atrial fibrillation patients. It prevents the blood clot and helps to reduce the risk of stroke.

Warnings and Precautions

Caution should be exercised in patients with history of stomach bleeding, kidney disease, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding.
Avoid abrupt withdrawal; otherwise it may lead to increased risk of stroke.
♦ Patient may develop with increased risk of bleeding; if it is so consult with your doctor.

Storage Conditions

Store it at room temperature (25°C), and in an airtight container. Protect from moisture.

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Recommended Reading

Stroke

Stroke can cause permanent disability and it is important to recognize its early warning signs to stop its progress. Early warning signs of stroke include sudden weakness of facial muscles.

Atrial Fibrillation

Atrial fibrillation may not be life threatening in itself but it is important to understand the causes, symptoms and treatments because of the risk of life threatening complications.

Common Side Effects of Anticoagulants / Blood Thinners

The main side effect of anticoagulants or blood thinners is bleeding. Others include reduced platelet counts, allergic reactions and skin necrosis.

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