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Palbociclib : Interaction with Food and Herbs


Interaction of Palbociclib with Food and Herbs - For your own safety It is important to understand and avoid the drug-food interaction and how to take the medication. Drug-food interaction can sometimes cause side effects and can even reduce the efficacy of the drug.
Palbociclib Palbociclib is a kinase inhibitor which is prescribed along with letrazole (an aromatase inhibitor) for the treatment of certain type of hormone receptor positive breast cancer (estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer) in postmenopausal women that is in an advanced stage or has spread to other parts of the body. It is also used along with fulvestrant in women in whom the cancer continues to worsen despite hormonal treatment. Palbociclib blocks the action of a specific protein that plays a role in the multiplication of cancer cells.

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Palbociclib Interactions with Food and Herbs

Grapefruit Juice: Intake of grapefruit juice with palbociclib might increase the plasma concentration of the drug.
St. John's Wort: Being an enzyme inducer, St. John's Wort might decrease the serum drug level of palbociclib.
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How to Take the Medication -

Palbociclib comes in the form of a capsule to be taken orally by mouth along with food. It is usually taken in combination with letrazole or fulvestrant for the treatment of breast cancer. Swallow the capsule as a whole. Do not ingest the capsule if it is found to be cracked or broken. Do not take extra dose to compensate the missed dose.
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