Food and Herbs Interaction with Palbociclib

Last Updated on Jun 09, 2023

Are you taking Palbociclib? Are you aware of the dangers of combining Palbociclib with certain foods and herbs? Drug-food-interactions are seldom discussed but can lead to undesirable side effects and potentially diminish the efficacy of the medication.

Palbociclib Interactions with Food and Herbs

Grapefruit Juice: Intake of grapefruit juice with palbociclib might increase the plasma concentration of the drug.
St. John's Wort: Being an enzyme inducer, St. John's Wort might decrease the serum drug level of palbociclib.

When and How to Take Palbociclib

Palbociclib comes in the form of a capsule to be taken orally by mouth along with food. It is usually taken in combination with letrazole or fulvestrant for the treatment of breast cancer. Swallow the capsule as a whole. Do not ingest the capsule if it is found to be cracked or broken. Do not take extra dose to compensate the missed dose.

Drug Name : Palbociclib

Palbociclib is a kinase inhibitor which is prescribed along with letrazole (an aromatase inhibitor) for the treatment of certain type of hormone receptor positive breast cancer (estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer) in postmenopausal women that is in an advanced stage or has spread to other parts of the body. It is also used along with fulvestrant in women in whom the cancer continues to worsen despite hormonal treatment. Palbociclib blocks the action of a specific protein that plays a role in the multiplication of cancer cells.

We recommend consulting your doctor to verify the information presented on this page or if you need any further clarifications.

Learn More about Drug-Food Interactions to Safeguard Your Health

1	Be Aware of Common Drug-Food Interactions

2	Grapefruit Can Work Against Your Drug

3	Interaction of Antibiotics with Dairy Products

4	Drug Interaction with Alcohol

5	Test Your Knowledge on Drug Interaction

6	Ten Common Drug-Drug interactions