Nifedipine Interactions with Food and HerbsPleurisy Root: Pleurisy root is not recommended with most cardiovascular medications due to the presence of cardiac glycosides in the pleurisy root.
Grapefruit and Juice: Don't take grapefruit and its juice when you are on nifedipine. This combination may alter the effectiveness of the drug.
St. John's Wort: St. John's Wort can alter the blood level of nifedipine and should therefore be avoided with it.
Tobacco: Cigarette smoking will decrease the effectiveness of the drug in conditions like angina. Those who take nifedipine should not use tobacco products.