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Drug information on P -Carzine (Procarbazine) from Alkem Laboratories Ltd. (Cytomed)

P -Carzine

Alkem Laboratories Ltd. (Cytomed)
Generic : Procarbazine
10 Capsules
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Drug Name : Procarbazine

Procarbazine(Matulane) generic P -Carzine is an antineoplastic agent, prescribed for Hodgkin disease. It inhibits protein, RNA, and DNA synthesis that help to stop the cancer cell growth.
More Info about Procarbazine

Other Trade Names for Procarbazine

India : 

International : 

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team on February, 2, 2017

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Medical Condition(s) for which P -Carzine may be prescribed

Side effects of P -Carzine

   Blood : Nose bleed, bruising, anemia and eosinophilia.

   Gastrointestinal : Liver dysfunction, jaundice, mouth ulcer, blood vomiting, blood in stool, diarrhea, indigestion, loss of appetite, abdominal pain, constipation and dry mouth.

   Central Nervous System : Coma, convulsions, nerve disease, incoordination, tingling, night blindness, diminished reflexes, falling, foot drop, headache, dizziness and unsteadiness.

   Heart : Low blood pressure, fast heart rate and fainting.

   Eye : Eye bleeding, sensitivity to light, double vision, optic disc swelling and inability to focus.

   Respiratory : Lung inflammation/infection and increased cough.

   Skin : Skin inflammation, itching, hair loss, pigmentation, rash, hives and flushing.

   Allergic reactions : Generalized allergic reactions.

   Genitourinary : Blood in urine, urinary frequency, nighttime urination and breast enlargement in male.

   Musculoskeletal : Pain, including muscle and joint pain and tremors.

   Psychiatric : Hallucinations, depression, apprehension, nervousness, confusion and nightmares.

   Miscellaneous : Infections, hearing loss, fever, increased sweating, lethargy, weakness, fatigue, edema, chills, sleeplessness, slurred speech, hoarseness and drowsiness.

Dosage & When it is to be taken (Indications)

Adult: The recommended dose is 2–4 mg/kg/day either in a single dose or divided, given for 7 days then increased to 4–6 mg/kg/day.

How to use P -Carzine?

It comes as a capsule to take by mouth, with or without food.

When is P -Carzine not to be taken? (Contraindications)

Contraindicated in patients with bone marrow depression and hypersensitivity.

Warnings and Precautions for P -Carzine

Caution should be exercised in patients with history of congestive heart failure, adrenal gland tumors (eg, pheochromocytoma), bone marrow depression, heart disease, frequent headaches, mental problems, kidney, or liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.

• Avoid exposure to sunlight.

• It may reduce platelet counts, avoid bruising or injury.

Other Precautions for P -Carzine

Avoid excess dosage.

Storage Conditions for P -Carzine

Store it at room temperature.

Schedule : G  Drugs that are to be used only under medical supervision.

Disclaimer : updates the prices regularly, however despite that there may be discrepancies in the prices displayed. This can be due to many reasons including -
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  • Change in price by the company
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For the above reasons Medindia cannot be held liable for any action taken based on the information provided by its website. The purpose of this website is to only provide the initial guidance and it does not intend to replace professional medical opinion in any manner whatsoever.

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