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Goustat is a xanthine oxidase (XO) inhibitor, prescribed for gout and hyperuricemia (high level of uric acid in blood). It decreases the amount of uric acid in blood. 

Drug information on Goustat (Febuxostat) from Alembic Chemical Works Co Ltd

Goustat

  Tablet  
Alembic Chemical Works Co Ltd
Generic : Febuxostat
 53.00
40mg
10 Tablets
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Medical Condition(s) for which Goustat may be prescribed


Overview of Goustat

The US FDA created an alert about the use of Febuxostat in Nov 2017. Febuxostat was approved in 2009 for treating gouty arthritis in adults but required the manufacturer to conduct a safety study as the drug label already carries a warning and precaution related to cardiovascular deaths.
The clinical trial was conducted in 6000 patients with gout treated with febuxostat compared to allopurinol. Febuxostat showed an increased risk of heart attacks, stroke, and heart-related deaths.
Healthcare professionals should always consider this FDA alert for safety reasons whether febuxostat needed to be prescribed. It is also advised that patients also should discuss with the physician or pharmacist in case they have any queries about the safety of febuxostat.
FDA is evaluating the safety of Febuxostat on a continuous basis and will update the public with necessary information. However, healthcare professionals and patients are requested to report for any side effects of febuxostat to the FDA MedWatch program.

Side effects of Goustat

  Most Common: Swelling in the face, lips, tongue or throat regions, sweating, general illness and loss of appetite.

  Skin: Allergic reactions.

  Respiratory : Difficulty in breathing.

  Heart: Chest pain and heaviness in the chest region.

  Gastrointestinal : Nausea and stomach pain.

  Central Nervous System: Headache and confusion.

  Eye: Vision problems.

  Genitourinary: Dark colored urine.

  Less Common: Anemia, pain, swelling in the joint regions, stroke and inflammation of liver.

  Liver: Liver failure and jaundice.

Dosage & When it is to be taken (Indications)

PO- The recommended dose is 40 to 80mg, once daily.

How to use Goustat?

It comes as a tablet to take by mouth with or without food.

When is Goustat not to be taken? (Contraindications)

Contraindicated in patients treated with azathioprine, mercaptopurine or theophylline.

Warnings and Precautions for Goustat

Caution should be exercised in patients with history of liver, kidney diseases, chest pain, cancer, stroke, elderly, children, pregnancy, and breastfeeding.

• Caution should be exercised in patients who have undergone organ transplantation (kidney, liver, heart and lung).

• If condition worsens, stop the medication immediately.

Other Precautions for Goustat

Patient may develop with severe blood clot events; if so contact your healthcare provider immediately.

Storage Conditions for Goustat

Store it at room temperature.

♦ Safety Labeling Changes Approved By FDA



Disclaimer : The Price of the drugs indicated above may not match the actual price at which they are sold. Prices can change depending on many factors, including GST. These are only approximate indicative prices of the drug.
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Substitutes for Goustat

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