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Zileuton - Indications, Dosage, Side Effects and Precautions

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Information about Zileuton

Generic Name : Zileuton
Up-to-date prescription details regarding Zileuton are provided here.

Pronunciation : zye-LOO-ton

Learn the correct pronunciation of the Zileuton, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y45.9 Therapeutic Classification : Anti- Inflammatory Agents

Trade Names/Brand Names of Zileuton

International :


Zyflo, Zyflo Cr

Why is Zileuton Prescribed? (Indications)

This medication is a leukotriene synthesis inhibitor, prescribed for asthma. It blocks the formation of a substance called leukotriene that helps to remove asthma and allergic symptoms.

When should Zileuton not be taken? (Contraindications)

Contraindicated in patients with liver disease and hypersensitivity.

What is the dosage of Zileuton?

PO- The recommended dose is 1200mg two times per day.

How should Zileuton be taken?

It comes as a tablet to take by mouth, within one hour after the morning and evening meals.

What are the warnings and precautions for Zileuton?

• Caution should be exercised in patients with history of mental illness, liver impairment, who are taking other medications, any allergy, during pregnancy and breastfeeding.

• Avoid alcohol consumption while taking this medication.

• Patient may develop with mental or mood changes or suicidal thoughts; watch them carefully.

• Continue the use of inhalers if you have used it before the treatment.

• Monitor liver functions regularly while taking this medication.

It should not be used in children less than 12 years old.

What are the side effects of Zileuton?

Most Common- Inflammation of sinus, nausea and throat pain.
Gastrointestinal- Abdominal pain, diarrhea, indigestion and vomiting.
Miscellaneous- Rash, severe allergic reactions and liver damage.

What are the other precautions for Zileuton?

Monitor liver functions regularly while taking this medication.

What are the storage conditions for Zileuton?

Store it at controlled room temperature (20 and 25°C) and in an airtight container. Keep away from children.
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