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Vildagliptin - Indications, Dosage, Side Effects and Precautions

Vildagliptin Medication Information

Discover comprehensive details about Vildagliptin, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Vildagliptin brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Vildagliptin
ICD Code : Y42.3 Therapeutic Classification : Antidiabetics

Brand Names or Trade Names of Vildagliptin

India :

International :


Eucreas, Galvumet, Galvus, Icandra, Jalra, Xiliarx

Why is Vildagliptin Prescribed? (Indications)

This medication is an oral antidiabetic agent, prescribed for type 2 diabetes mellitus along with other medications. It works by increasing the amount of two incretin hormones in the body that are produced naturally by the body in response to food intake.

When should Vildagliptin not be taken? (Contraindications)

Contraindicated in patients with type 1 diabetes, diabetic ketoacidosis, severe liver impairment, during pregnancy and breastfeeding.

What is the dosage of Vildagliptin?

PO- with metformin or a thiazolidinedione: 50 mg twice daily; with a sulfonylurea: 50 mg/day in the morning. Maximum: 100 mg/day.

How should Vildagliptin be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Vildagliptin?

• Caution should be exercised in patients with history of severe kidney disease.

• It may cause dizziness or fatigue, do not drive a car or operate machinery while taking this medication.

• Patient may develop with increased risk of foot ulcers and blistering of the skin; if it is so consult with your doctor.

• Monitor liver function and blood sugar level regularly while taking this medication.

What are the side effects of Vildagliptin?

Most Common - Low blood sugar level, tremor, headache, weight gain and fluid retention.
Central Nervous System - Dizziness, fatigue, and feeling weak.

What are the other precautions for Vildagliptin?

Avoid excess dosage.

What are the storage conditions for Vildagliptin?

Store it at room temperature (25 to 30°C).

Vildagliptin : Frequently Asked Questions

Q: Does Vildagliptin affect blood pressure?

A: Vildagliptin promotes vascular relaxation and lowers both systolic and diastolic blood pressure. Vildagliptin causes an increase in heart rate in type 2 diabetes patients(1 Trusted Source
Vasculoprotective Effects of Vildagliptin. Focus on Atherogenesis

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).

Q: Does Vildagliptin affect cholesterol levels?

A: Vildagliptin showed a significant reduction in total cholesterol, low density lipoproteins(LDL), and triglycerides(2 Trusted Source
Efficacy and short-term side effects of sitagliptin, vildagliptin and saxagliptin in Chinese diabetes: a randomized clinical trial

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).

Q: Can Vildagliptin and Metformin be taken together?

A: Vildagliptin, as monotherapy and in combination with metformin, is an effective therapy for lowering HbA1c, aiding in achieving target glycemic control, and is well tolerated in patients with Type 2 diabetes mellitus(3 Trusted Source
Data on vildagliptin and vildagliptin plus metformin combination in type-2 diabetes mellitus management

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).

Q: When is the best time to take Vildagliptin?

A: Vildagliptin can be taken once or twice per day. Although evening vildagliptin dosing was as effective as morning dosing in patients with type 2 diabetes, evening dosing may be slightly more effective for night-time glucose reduction. Both regimens were equally effective in lowering postprandial glucose in type 2 diabetes patients(4 Trusted Source
Hormonal and metabolic effects of morning or evening dosing of the dipeptidyl peptidase IV inhibitor vildagliptin in patients with type 2 diabetes

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).

Q: Is Vildagliptin safe in elderly patients?

A: Vildagliptin monotherapy was effective and well tolerated in the treatment of elderly patients. No dose adjustments are necessary for vildagliptin in elderly patients(5 Trusted Source
Management of type 2 diabetes in treatment-naive elderly patients: benefits and risks of vildagliptin monotherapy

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).



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