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General Information on Vigabatrin

Generic Name : Vigabatrin

Pronunciation : vye-GA-ba-trin

Latest prescription information about Vigabatrin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y46.6 | Therapeutic Classification : Anticonvulsants

Trade Names/Brand Names of Vigabatrin

India : 

International : 

Sabril

Why is Vigabatrin Prescribed? (Indications)

This medication is an antiepileptic agent, prescribed for seizures. It works by decreasing abnormal electrical activity in the brain.

When should Vigabatrin not to be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Vigabatrin?

PO- Initial: The recommended dose is 50 mg/kg/day in two divided doses and can be titrated by 25-50 mg/kg/day increments every 3 days up to a maximum of 150 mg/kg/day.

How should Vigabatrin be taken?

It comes as a solution to take by mouth twice daily, with or without food.

What are the warnings and precautions for Vigabatrin?

Caution should be exercised in patients with history of kidney or liver impairment, vision problem, suicidal thoughts, depression, any allergy, who are taking other medication, elderly, during pregnancy and breastfeeding.

It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

It may develop with unusual weight gain; if it is so consult with your doctor.

It may develop with increased risk of suicidal thoughts; watch them carefully.

Perform eye examination regularly while taking this medication.

What are the side effects of Vigabatrin?

  Most Common: Headache, drowsiness, fatigue, dizziness, seizures, increased weight, upper respiratory tract infection, visual defects, depression, tremor, night blindness, nausea, diarrhea, memory loss, sleeplessness, irritability, abnormal coordination, blurred vision, double vision, vomiting, influenza, fever and rash.
  Eye : Eye infection.
  Gastrointestinal : Vomiting, constipation and diarrhea.
  General : Fever.
  Infections : Upper respiratory tract infection, ear infection, viral infection, fungal infection, inflammation of stomach/sinus and urinary tract infection.
  Metabolic : Decreased appetite.
  Central Nervous System : Sedation, drowsiness, epilepsy, mental weakness, muscle weakness, irritability and sleeplessness.
  Respiratory : Nasal congestion and cough.

What are the other precautions for Vigabatrin?

Avoid alcohol consumption.

What are the storage conditions for Vigabatrin?

Store it at room temperature (20-25 C), and in an airtight container.

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