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General Information on Treprostinil

Generic Name : Treprostinil

Pronunciation : treh-PRAW-steh-nil

Latest prescription information about Treprostinil. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y44.2 | Therapeutic Classification : Anticoagulants / Antithrombotics

Trade Names/Brand Names of Treprostinil

India- Prostonil.
International- Remoludin, Tyvaso.

Why is Treprostinil Prescribed? (Indications)

This medication is a synthetic analogue of prostacyclin, prescribed for pulmonary atrial hypertension (high blood pressure in the lungs). It relaxes the blood vessels and thereby allows easy blood flow.  

When should Treprostinil not to be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Treprostinil?

SC/IV: Initial dose: 1.25 mg/kg/min; reduce to 0.625 mg/kg/min if initial dose is not tolerated.

How should Treprostinil be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein or under the skin.

What are the warnings and precautions for Treprostinil?

Caution should be exercised in patients with history of liver, kidney, bleeding problems, low blood pressure, during pregnancy and breastfeeding.

It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

What are the side effects of Treprostinil?

  Severe: Requires narcotics and discontinuation of medicine.
  Local: Pain, swelling, rash and itching.
  Respiratory : Breathing problems, cough and throat irritation.
  Musculoskeletal : Jaw or bone pain.
  Gastrointestinal : Nausea, vomiting and diarrhea.
  Heart: Palpitations and heart attack.
  Central Nervous System: Dizziness and tiredness.

What are the other precautions for Treprostinil?

Avoid alcohol consumption.
Avoid excess dosage.

What are the storage conditions for Treprostinil?

Store it at room temperature (15 to 25C).

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