Email Print This Page Comment bookmark
Font : A-A+

Consumer    Professional

General Information on Topotecan

Generic Name : Topotecan

Pronunciation : toe'' poe tee' kan

Latest prescription information about Topotecan. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Trade Names/Brand Names of Topotecan

India : 

International : 

Hycamtin

Why is Topotecan Prescribed? (Indications)

This medication is a topoisomerase type I inhibitor, prescribed for ovarian or lung cancer that do not respond well to other types of cancer treatment. It kills the cancer cells in ovary and lungs. 

When should Topotecan not to be taken? (Contraindications)

Contraindicated in pregnant and breastfeeding women, and hypersensitivity.

What is the dosage of Topotecan?

IV- The recommended dose is 1.5 mg/m2/day over 30 minutes, on 1 to 5 days. It is given in uterus and small cell lung cancer as an IV infusion in a dose of 1.5 mg/m2/day for the first 5 days of a 21-day course. The patient has to undergo at least 4 courses.
In cancer of the cervix a dose of 0.75 mg/m2 is given for 3 days along with cisplatin on the first day of a 21-day course.

How should Topotecan be taken?

This medication available in the form of capsule to take by mouth with a full glass (8 ounces) of water, with or without food. (Swallow whole, do not open/ chew/ crush.)
Injection: Intravenously (into a vein) over 30 minutes by healthcare providers.

What are the warnings and precautions for Topotecan?

• Caution needed for patients with history of pre existing bone marrow depression.

• Frequent monitoring of blood counts during treatment.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

What are the side effects of Topotecan?

  Central Nervous System: Fatigue, weakness, discomfort,headache.
  Blood: Abnormal low white blood cell count, hemoglobin.
  Miscellaneous: GI upset, total hair loss, shortness of breath, itching and increased levels of bilirubin.

What are the other precautions for Topotecan?

Avoid alcoholic beverages while taking this medication.

What are the storage conditions for Topotecan?

Intravenous: Unopened vial: Store at 20-25°C; protect from light. Reconstituted solution: Stable for 24 hour at 20-25°C in ambient light.

Advertisement

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions
Buy Medicines (Drug) at Concessional Price from India

Drugs A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Drugs Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Stay Connected

  • Available on the Android Market
  • Available on the App Store