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General Information on Tacrine

Generic Name : Tacrine

Pronunciation : tak-reen

Latest prescription information about Tacrine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y51.8 | Therapeutic Classification : Anti- Alzheimer's Agents

Trade Names/Brand Names of Tacrine

International- Cognex.

Why is Tacrine Prescribed? (Indications)

This medication is a cholinesterase inhibitor, prescribed for mild to moderate dementia. It increases the amount of acetylcholine in the brain.

When should Tacrine not to be taken? (Contraindications)

Contraindicated in patients previously treated with this medication, who have too much bilirubin in blood, and hypersensitivity.

What is the dosage of Tacrine?

Adults—Initial- 10 milligrams (mg) four times a day. Maximum: 40 mg four times a day.

How should Tacrine be taken?

It comes as a capsule to take by mouth, on an empty stomach.

What are the warnings and precautions for Tacrine?

• Caution should be exercised in patients with history of ulcers, seizures, problems with urinary system, asthma, blood vessel problems, heart, kidney, liver, lung or stomach disorders.

• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

What are the side effects of Tacrine?

  Most Common: Increase in liver test called alanine aminotransferase (ALT), nausea, vomiting, diarrhea, indigestion, muscle pain, loss of appetite and unsteadiness.
  Body As A Whole : Headache, fatigue, chest pain, decrease in weight, back pain and weakness.
  Gastrointestinal : Loss of appetite, abdominal pain, flatulence and constipation.
  Blood : Bruising.
  Musculoskeletal: Muscle pain.
  Central Nervous System: Dizziness, confusion, unsteadiness, sleeplessness, drowsiness, tremor, agitation, depression, abnormal thinking, anxiety and hallucinations.
  Respiratory : Nose inflammation, upper respiratory infection and coughing.
  Skin: Rash, facial flushing and skin flushing.
  Genitourinary: Urination frequency, urinary tract infection and urinary incontinence.

What are the other precautions for Tacrine?

Avoid excess dosage.

What are the storage conditions for Tacrine?

Store it at room temperature (15-30°C) and in an airtight container.

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