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Sitagliptin - Indications, Dosage, Side Effects and Precautions

Sitagliptin Medication Information

Learn everything you need to know about Sitagliptin-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Sitagliptin brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Sitagliptin
Pronunciation : sit a glip' tin
ICD Code : Y52.6 Therapeutic Classification : Antihyperglycemics

Brand Names or Trade Names of Sitagliptin

India :

International :


Januvia Tab, Zita, Istavel

Why is Sitagliptin Prescribed? (Indications)

Sitagliptin is indicated to improve glucose control in adults with type 2 diabetes mellitus along with diet and exercise.

When should Sitagliptin not be taken? (Contraindications)

• There is a previous history of a severe allergy to Sitagliptin
• Patients with type 1 diabetes
• Diabetic ketoacidosis
• Previous history of pancreas inflammation

What is the dosage of Sitagliptin?

Sitagliptin is available as an oral tablet.
Strengths: 50mg, 100mg

How should Sitagliptin be taken?

It should be taken by mouth once daily with or without food.
The dose is 25-50mg in patients with kidney problems

What are the warnings and precautions for Sitagliptin?

•1. Avoid alcohol consumption while taking Sitagliptin

• 2. Sitagliptin may lead to low blood sugar, monitor blood sugar regularly.

What are the side effects of Sitagliptin?

Metabolic- Low blood sugar with other medications.
Central Nervous System- Headache.
Eye and ENT- Inflammation of nasopharynx.
Gastrointestinal- Diarrhea, nausea, inflammation of pancreas.
Respiratory- Upper respiratory tract infection.
Musculoskeletal-Joint pain, muscle pain, pain in extremity and back pain.

What are the other precautions for Sitagliptin?

Caution is needed in patients with:
• Patients under 18 years of age
• Kidney problems
• Liver problems
• Pancreas problems
• Pregnant and lactating women

What are the Drug Interactions of Sitagliptin?

Do not take Sitagliptin with:
• Digoxin
• Sulphonylureas
• Insulin

What are the storage conditions for Sitagliptin?

Store it at room temperature and in an airtight container. Keep away from children.

Sitagliptin : Frequently Asked Questions

Q: Can Sitagliptin be used as monotherapy?

A: Sitagliptin is an oral hypoglycemic drug that can be used alone or in combination with other medications to treat type 2 diabetes, such as metformin or thiazolidinediones(1 Trusted Source
Sitagliptin: a novel drug for the treatment of type 2 diabetes

Go to source
).

Q: Does Sitagliptin cause weight loss?

A: Sitagliptin does not cause weight loss or gain. It has weight neutral properties. Sitagliptin, when combined with metformin, has a weight-reducing effect in overweight or obese cases of type 2 diabetes(2 Trusted Source
Sitagliptin: a review

Go to source
).

Q: Does Sitagliptin cause pancreatitis?

A: Sitagliptin is significantly associated with an increased risk of acute pancreatitis. If pancreatitis is suspected, sitagliptin should be discontinued immediately(3 Trusted Source
Sitagliptin-induced pancreatitis - a longer road than expected

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).

Q: When is the best time to take Sitagliptin?

A: Sitagliptin is usually taken once daily with or without food. Sitagliptin should be taken every day at the same time(4 Trusted Source
Sitagliptin

Go to source
).

Q: Does Sitagliptin cause hypoglycemia?

A:  Sitagliptin alone does not cause hypoglycemia(low blood sugar). Sitagliptin may cause hypoglycemia when combined with other hypoglycemic agents(5 Trusted Source
Sitagliptin

Go to source
).


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