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General Information on Quinupristin and Dalfopristin

Generic Name : Quinupristin and Dalfopristin

Pronunciation : KWIN-ue-PRIS-tin-DAL-foe-PRIS-tin

Latest prescription information about Quinupristin and Dalfopristin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y41.8 | Therapeutic Classification : Anti- Infectives

Trade Names/Brand Names of Quinupristin and Dalfopristin

International- Synercid.

Why is Quinupristin and Dalfopristin Prescribed? (Indications)

This medication is a streptogramin antibiotic, prescribed for certain bacterial infection (e.g. complicated skin and skin structure infections). It fights bacteria in the body.

When should Quinupristin and Dalfopristin not to be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Quinupristin and Dalfopristin?

IV- The recommended dose is 7.5 mg/kg two times per day.

How should Quinupristin and Dalfopristin be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Quinupristin and Dalfopristin?

Caution should be exercised in patients with history of liver or kidney impairment, stomach or bowel problems, HIV infection, high blood bilirubin levels, heart disease, who are taking other medications, any allergy, children, during pregnancy and breastfeeding.

Avoid long-term use of this medication.

Avoid becoming dehydrated.

What are the side effects of Quinupristin and Dalfopristin?

   Body as a Whole : Pain at injection site, abdominal pain, worsening of underlying illness, allergic reaction, chest pain, fever, infection.
   Heart : Fluid retention, palpitation, vein inflammation.
   Gastrointestinal : Nausea, vomiting, constipation, indigestion, mouth infection, inflammation of pancreas, mouth ulcer.
   Metabolic : Gout, swelling in the extremities.
   Musculoskeletal : Joint pain, muscle pain, muscle spasm.
   Central Nervous System : Headache, anxiety, confusion, dizziness, increased muscle tone, sleeplessness, leg cramps, tingling, dilatation of blood vessels.
   Respiratory : Difficulty in breathing, lung infection.
   Skin : Rash, sweating, hives.
   Genitourinary : Blood in urine, vaginal inflammation.

What are the other precautions for Quinupristin and Dalfopristin?

Avoid excess dosage.

What are the storage conditions for Quinupristin and Dalfopristin?

Store it in refrigerator (2 to 8C).

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