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Prochlorperazine - Indications, Dosage, Side Effects and Precautions

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Prochlorperazine Medication Information

Learn everything you need to know about Prochlorperazine-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Prochlorperazine brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Prochlorperazine
Pronunciation : proe klor per' a zeen
ICD Code : Y43.0 Therapeutic Classification : Antiemetics

Brand Names or Trade Names of Prochlorperazine

India :

International :


Compro, Procomp

Why is Prochlorperazine Prescribed? (Indications)

This medication is a tranquilizer, prescribed for schizophrenia, severe nausea and vomiting.

When should Prochlorperazine not be taken? (Contraindications)

Contraindicated in patients with CNS depression, children less than 2 years old, and hypersensitivity.

What is the dosage of Prochlorperazine?

Nausea and Vomiting - Oral Dosage: Tablets: Take one 5 mg or 10 mg tablet 3 or 4 times daily.
Rectal Dosage: 25 mg twice daily.
I.M. Dosage: Initially 5 to 10 mg (1 to 2 mL) injected deeply.
Adult Psychiatric Disorders- Oral Dosage: The recommended dosage is 5 mg 3 or 4 times daily.

How should Prochlorperazine be taken?

It comes as a tablet, capsule, liquid to take by mouth, with or without food.
It also comes as a solution for injection to be administered by a healthcare provider into the vein or muscle.
It also comes as rectal suppositories, to insert through the rectum.

What are the warnings and precautions for Prochlorperazine?

• Caution should be exercised in patients with history of heart disease, central nervous system depression, liver problems, low blood pressure, increased eye pressure, neuroleptic malignant syndrome, tardive dyskinesia, bone marrow depression, involuntary muscle movements, Parkinson disease, Reye syndrome, prostate enlargement, seizures, alcoholism, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.

• It may cause drowsiness, dizziness, blurred vision or lightheadedness, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

• Avoid exposure sunlight.

What are the side effects of Prochlorperazine?

Most Common - Drowsiness, dizziness, absence of menstrual periods, blurred vision, skin reactions and Neuroleptic Malignant Syndrome (NMS).
Gastrointestinal - Nausea, constipation and bowel obstruction.
Genitourinary - Ejaculatory disorders/impotence, painful erection, lazy colon, urinary retention, menstrual irregularities and false-positive pregnancy tests.
Heart - Low blood pressure and heart arrest.
Blood - Blood dyscrasias.
Liver - Jaundice and liver damage.
Metabolic - Increased appetite and increased weight.

What are the other precautions for Prochlorperazine?

Avoid excess dosage.

What are the storage conditions for Prochlorperazine?

Store it at controlled room temperature (15° and 30°C).

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