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General Information on Phylloquinone

Generic Name : Phylloquinone

Pronunciation : fye-toe-na-DYE-one

Latest prescription information about Phylloquinone. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y44.2 | Therapeutic Classification : Anticoagulants / Antithrombotics

Trade Names/Brand Names of Phylloquinone

India- Injek Vial, Kenadion Inj.
International- Mephyton.

Other Name(s) of Phylloquinone

Phytonadione, Vitamin K.

Why is Phylloquinone Prescribed? (Indications)

This medication is often known as vitamin K1, prescribed for coagulation disorders (bleeding problems) in patients with vitamin K deficiency (e.g.,anticoagulant-induced prothrombin deficiency, hypoprothrombinemia). It helps the liver to produce blood-clotting factors.  

When should Phylloquinone not to be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Phylloquinone?

IV- Initial: The recommended dose is 2.5 mg-10 mg or up to 25 mg (rarely 50 mg)

How should Phylloquinone be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Phylloquinone?

• Caution should be exercised in patients with history of liver or kidney problems, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.

• Avoid large dose in newborns; otherwise it will cause severe anemia.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

What are the side effects of Phylloquinone?

•  Most Common: Severe life threatening allergic reactions, pain, swelling or tenderness at the injection site.
•  Miscellaneous: Dizziness, “blue baby" who has a heart malformation, difficulty in breathing, sweating and low blood pressure.

What are the other precautions for Phylloquinone?

Monitor prothrombin time (blood clotting time) regularly while taking this medication.

What are the storage conditions for Phylloquinone?

Store it at controlled room temperature (15-30°C), and in an airtight container.

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