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Phenylephrine - Indications, Dosage, Side Effects and Precautions

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Information about Phenylephrine

Generic Name : Phenylephrine
Up-to-date prescription details regarding Phenylephrine are provided here.

Pronunciation : FEN-il-EF-rin

Learn the correct pronunciation of the Phenylephrine, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y55.5 Therapeutic Classification : Decongestants

Trade Names/Brand Names of Phenylephrine

India :

International :


Deconsal CT , Histinex HC , Neo-Synephrine .

Why is Phenylephrine Prescribed? (Indications)

This medication is a selective alpha agonist, used to increase blood pressure and topically as a nasal decongestant. It is also used in the eye to dilate the pupil or to constrict superficial blood vessels in eye allergy. It works by reducing swelling of the blood vessels in the nasal passages.

When should Phenylephrine not be taken? (Contraindications)

Contraindicated in patients with increased blood pressure, increase in heart rate, raised eye pressure. It should not be used with a MAO inhibitor.

What is the dosage of Phenylephrine?

The recommended dose is:
IM- 2 to 5 mg.
IV- 0.1 to 0.5mg by slow infusion.
PO- 5 to 10mg.
Nasal- Nasal congestion: As 0.25-1% solution: Instill/spray 4 hourly as needed.
Ophthalmic- Usually 0.12% solution: Instill 1-2 drops ≤4 times/day for ≤72 hour.

How should Phenylephrine be taken?

It comes as a tablet, a liquid, or a dissolving strip to take by mouth. It is also comes as eye drops and nasal solution, instilled over affected area.

What are the warnings and precautions for Phenylephrine?

•Do not give phenylephrine containing products to children younger than 4 years of age. It may cause serious side effects or cause of death in children.

• Do not use this medication for longer duration, it may cause rebound congestion in prolonged or excessive use of nasal or eye drops.

• Caution should be exercised in patients with history of severe increase in thyroid hormone, severe heart disease, diabetes, prostate enlargement, during pregnancy and breastfeeding.

What are the side effects of Phenylephrine?

Skin- Hives, itching, rash, photosensitivity.
Heart- High blood pressure, abnormal heart rhythm.
Central Nervous System - Tremor, irritability, sleeplessness, weakness, nervousness, headache.
EYE- Blurring of vision, stinging or burning sensation in the eye due to eye drops.
Respiratory - Tightness of the chest and wheezing, shortness of breath.

What are the other precautions for Phenylephrine?

Instill properly as directed by your physician.

What are the storage conditions for Phenylephrine?

Refer to the package insert. Some products are stored at room temperature whereas some are stored under refrigeration.
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