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General Information on Phentolamine Mesylate

Generic Name : Phentolamine Mesylate

Pronunciation : fen-TOL-a-meen MES-i-late

Latest prescription information about Phentolamine Mesylate. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y57.6 | Therapeutic Classification : Diagnostic Agents

Trade Names/Brand Names of Phentolamine Mesylate

India : 

International : 

Rogitine, Phentolamine Mesylate

Why is Phentolamine Mesylate Prescribed? (Indications)

This medication is a reversal anesthesia used in dental procedures for anesthetizing soft tissues (lip and tongue). It is an antihypertensive, prescribed for prevention or control of hypertension. Not recommended for children less than 6 years and weight less than 15kg (33lbs).  

When should Phentolamine Mesylate not to be taken? (Contraindications)

Contraindicated in patients with heart attack, fast heart rate, and hypersensitivity to this drug.

What is the dosage of Phentolamine Mesylate?

Adult: IV- The recommended dose is 2 to 5mg. Repeat if needed.

How should Phentolamine Mesylate be taken?

It comes as a solution for injection, administered by healthcare providers into the vein or muscle.

What are the warnings and precautions for Phentolamine Mesylate?

Caution should be exercised in patients with history of fast heart rate; peptic ulcer disease; pregnancy and breastfeeding.

Discontinue if symptoms of heart disease occur or worsen.

What are the side effects of Phentolamine Mesylate?

   Most Common: Sweating, feelings of apprehension, orthostatic hypotension (sudden decline in the blood pressure when a person stands up suddenly after long hours of rest), flushing, weakness, dizziness, facial swelling, jaw and oral pain.
   Heart: Fast heart rate, abnormal heart rhythm, chest pain.
   Respiratory : Nasal stuffiness.
   Gastrointestinal: Nausea, vomiting, diarrhea.
   Potentially Fatal: Heart attack, confusion, severe or sudden headache, sudden loss of coordination, sudden slurring of speech.

What are the other precautions for Phentolamine Mesylate?

Avoid using contaminated solution of this medication.

What are the storage conditions for Phentolamine Mesylate?

Injection: Use the reconstituted solution immediately after preparation and should not be stored. Store unopened vials at controlled room temperature (25C).

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