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Phentolamine Mesylate - Indications, Dosage, Side Effects and Precautions

Phentolamine Mesylate Medication Information

Learn everything you need to know about Phentolamine Mesylate-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Phentolamine Mesylate brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Phentolamine Mesylate
Pronunciation : fen-TOL-a-meen MES-i-late
ICD Code : Y57.6 Therapeutic Classification : Diagnostic Agents

Brand Names or Trade Names of Phentolamine Mesylate

India :

International :


Rogitine, Phentolamine Mesylate

Why is Phentolamine Mesylate Prescribed? (Indications)

This medication is a reversal anesthesia used in dental procedures for anesthetizing soft tissues (lip and tongue). It is an antihypertensive, prescribed for prevention or control of hypertension. Not recommended for children less than 6 years and weight less than 15kg (33lbs).

When should Phentolamine Mesylate not be taken? (Contraindications)

Contraindicated in patients with heart attack, fast heart rate, and hypersensitivity to this drug.

What is the dosage of Phentolamine Mesylate?

Adult: IV- The recommended dose is 2 to 5mg. Repeat if needed.

How should Phentolamine Mesylate be taken?

It comes as a solution for injection, administered by healthcare providers into the vein or muscle.

What are the warnings and precautions for Phentolamine Mesylate?

•Caution should be exercised in patients with history of fast heart rate; peptic ulcer disease; pregnancy and breastfeeding.

• Discontinue if symptoms of heart disease occur or worsen.

What are the side effects of Phentolamine Mesylate?

Most Common- Sweating, feelings of apprehension, orthostatic hypotension (sudden decline in the blood pressure when a person stands up suddenly after long hours of rest), flushing, weakness, dizziness, facial swelling, jaw and oral pain.
Heart- Fast heart rate, abnormal heart rhythm, chest pain.
Respiratory - Nasal stuffiness.
Gastrointestinal- Nausea, vomiting, diarrhea.
Potentially Fatal- Heart attack, confusion, severe or sudden headache, sudden loss of coordination, sudden slurring of speech.

What are the other precautions for Phentolamine Mesylate?

Avoid using contaminated solution of this medication.

What are the storage conditions for Phentolamine Mesylate?

Injection: Use the reconstituted solution immediately after preparation and should not be stored. Store unopened vials at controlled room temperature (25°C).

Phentolamine Mesylate : Frequently Asked Questions

Q: What are the uses of Phentolamine mesylate?

A: Phentolamine mesylate is used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma (1 Trusted Source
Phentolamine mesylate

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Q: Does Phentolamine mesylate increases heart rate?

A: When administered intravenously, phentolamine mesylate lowers the diastolic blood pressure while increasing the heart rate and cardiac output (2 Trusted Source
Circulatory and alpha-adrenoceptor blocking effects of phentolamine.

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Q: How does Phentolamine mesylate reduce blood pressure?

A: Phentolamine mesylate works by blocking alpha-adrenergic receptors, leading to muscle relaxation and a widening of the blood vessels. This results in a lowering of blood pressure (1 Trusted Source
Phentolamine mesylate

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Q: Is it safe to take Phentolamine mesylate during pregnancy?

A: Phentolamine mesylate should be used during pregnancy only if the potential benefit justifies the risk to the fetus (3 Trusted Source
PHENTOLAMINE MESYLATE- phentolamine mesylate injection

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).

Q: Who should not take Phentolamine mesylate?

A: Phentolamine mesylate is contraindicated in patients with heart conditions such as myocardial infarction, coronary insufficiency, angina, or other evidence suggestive of coronary artery disease (4 Trusted Source
Phentolamine Mesylate: Drug Dosages

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