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General Information on Pertuzumab

Generic Name : Pertuzumab

Latest prescription information about Pertuzumab. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y43.4 | Therapeutic Classification : Monoclonal antibodies

Trade Names/Brand Names of Pertuzumab

International- Perjeta.

Why is Pertuzumab Prescribed? (Indications)

This medication is a monoclonal antibody, prescribed for HER2-positive breast cancer (which is more aggressive) either alone or with other medications. It stops cancer cell growth.

When should Pertuzumab not to be taken? (Contraindications)

None.

What is the dosage of Pertuzumab?

IV- The recommended initial dose is 840 mg, followed every 3 weeks thereafter by a dose of 420 mg.

How should Pertuzumab be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Pertuzumab?

Caution should be exercised in patients with liver or kidney impairment, during pregnancy and breastfeeding.

Patient may develop with increased risk of ventricular dysfunction; monitor heart function regularly while taking this medication.

It may cause harm to fetus when it is administered to pregnant women; consult with your healthcare provider before taking this medication.

What are the side effects of Pertuzumab?

   Most Common : Diarrhea, hair loss, decrease in white blood cells, stomach upset, fatigue, rash, damage to the nerves.
   General : Fatigue, weakness, swelling in the extremities, fever.
   Skin: Hair loss, nail disorder, itching, dry skin.
   Gastrointestinal : Nausea, vomiting, constipation, mouth ulcer.
   Blood : Anemia.
   Central Nervous System : Headache, change in taste, dizziness, and sleeplessness.
   Musculoskeletal : Muscle pain, joint pain.
   Infections : Upper respiratory tract infection, nose inflammation.
   Respiratory : Difficulty in breathing.
   Metabolic : Decreased appetite.
   Eye : Increased tears.

What are the other precautions for Pertuzumab?

Avoid excess dosage.

What are the storage conditions for Pertuzumab?

Store vials in a refrigerator at 2C to 8C.

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