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Pentoxifylline - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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General Information on Pentoxifylline

Generic Name : Pentoxifylline
Pronunciation : pen tox I' fi leen
Latest prescription information about Pentoxifylline. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y44.2 | Therapeutic Classification : Anticoagulants / Antithrombotics
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Trade Names/Brand Names of Pentoxifylline

India : 

International : 

Pentoxil, Trental
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Why is Pentoxifylline Prescribed? (Indications)

This medication is a xanthine derivative, prescribed for intermittent claudication (pain, cramping, numbness, or weakness in the foot, hip, thigh, or buttocks) due to poor blood circulation. It decreases the thickness of blood.

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When should Pentoxifylline not be taken? (Contraindications)

Contraindicated in patients with recent stroke, intolerance to methylxanthines such as caffeine, theophylline, theobromine and hypersensitivity.

What is the dosage of Pentoxifylline?

PO- The usual dosage is one tablet (400 mg) three times a day with meals.

How should Pentoxifylline be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Pentoxifylline?

• Caution should be exercised in patients with history of ulcers, blood vessel problems, high blood pressure, kidney problems, bleeding in the eye, any allergy, who are other medications, during pregnancy and breastfeeding.

• It may cause dizziness or blurred vision, do not drive a car or operate machinery while taking this medication.

What are the side effects of Pentoxifylline?

•   Heart : Chest pain, abnormal heart rhythm, palpitations and flushing.
•   Gastrointestinal : Abdominal discomfort, belching, flatulence, diarrhea, indigestion, nausea and vomiting.
•   Central Nervous System : Agitation, nervousness, dizziness, drowsiness, headache, sleeplessness, tremor and blurred vision.

What are the other precautions for Pentoxifylline?

Avoid excess dosage.

What are the storage conditions for Pentoxifylline?

Store it at room temperature, away from direct sunlight.


<>Schedule : HPrescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.



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