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Pediarix Vaccine - Indications, Dosage, Side Effects and Precautions

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Information about Pediarix Vaccine

Generic Name : Pediarix Vaccine
Up-to-date prescription details regarding Pediarix Vaccine are provided here.

Pronunciation : dif-THEER-ee-a

Learn the correct pronunciation of the Pediarix Vaccine, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y59.9 Therapeutic Classification : Immunizing Agents

Trade Names/Brand Names of Pediarix Vaccine

International :


Pediarix, Kinrix

Why is Pediarix Vaccine Prescribed? (Indications)

This medication is an immunization agent, prescribed for diphtheria, tetanus, pertussis, hepatitis B and polio infections in infants and children.  Pediarix works by exposing child to a small dose of the bacteria or a protein from the bacteria or virus, which causes the body to develop immunity to the disease.

When should Pediarix Vaccine not be taken? (Contraindications)

Contraindicated in patients with encephalopathy, progressive neurologic disorder, including infantile spasms, uncontrolled epilepsy due to previous administration of any pertussis-containing vaccine within 7 days and hypersensitivity.

What is the dosage of Pediarix Vaccine?

The primary immunization series is 3 doses of 0.5 mL, given intramuscularly, at 6- to 8-week intervals (preferably 8 weeks).

How should Pediarix Vaccine be taken?

It comes as a solution for injection to be administered by a healthcare provider into the large muscle.

What are the warnings and precautions for Pediarix Vaccine?

• Caution should be exercised in patients with history of fever, infection, cancer, received chemotherapy or radiation therapy, weakened immune system, central nervous system problems, bleeding problems, any allergy, who are taking other medications.

• It should not be used in children less than 6 weeks of age.

• Do not administer this medication subcutaneously or intravenously.

What are the side effects of Pediarix Vaccine?

Serious- Death, seizures and brain disorder.
Heart- Blue baby.
Gastrointestinal- Diarrhea and vomiting.
General- Fatigue, limb swelling, fever and sudden infant death syndrome.
Injection site reactions- Itching, in duration, nodule/lump, pain, redness, swelling, warmth and irritability.
Immune- Severe allergic reactions.
Respiratory- Upper respiratory tract infection, cough and difficulty in breathing.
Liver- Abnormal liver function tests.
Metabolic- Loss of appetite.
Central Nervous System- Bony projection in head, convulsions, depressed level of consciousness, febrile convulsions, muscle weakness, lethargy and drowsiness.
Psychiatric - Crying, sleeplessness, nervousness, restlessness and screaming.
Skin- Redness, rash, hives, red spots and paleness.

What are the other precautions for Pediarix Vaccine?

Avoid excess dosage.

What are the storage conditions for Pediarix Vaccine?

Store it in refrigerator (2º and 8ºC), do not freeze it.
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