Nebivolol - Indications, Dosage, Side Effects and Precautions

Nebivolol Medication Information

Discover comprehensive details about Nebivolol, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Nebivolol brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Nebivolol

Pronunciation : ne-BIV-oh-lol

ICD Code : Y51.7 Therapeutic Classification : Anti- Hypertensives

Brand Names or Trade Names of Nebivolol

India :

More info >>>

International :

Bystolic

Why is Nebivolol Prescribed? (Indications)

Nebivolol is a beta-blocker, prescribed for hypertension either alone or combined with other medications. It is also used for some cases of heart failure. It decreases the amount of blood pumped out from heart. This helps to decrease blood pressure and reduces the workload on the heart.

When should Nebivolol not be taken? (Contraindications)

Nebivolol should not be used in patients allergic to the drug, with slow heartbeat, low cardiac output, or liver failure

What is the dosage of Nebivolol?

Hypertension- 5 to 40mg once daily.
Heart failure: 1.25-10 mg once daily.

How should Nebivolol be taken?

It comes as a tablet to take by mouth, with or without food once a day.

What are the warnings and precautions for Nebivolol?

•Avoid abrupt withdrawal of the drug.

The drug should be used with caution if the patient is having any of these conditions:

• Occasional numbness and tingling in the fingers.• Asthma.

• Chronic obstructive pulmonary disease (COPD).

• Diabetes, since it may mask the effects of low blood sugar levels.

• Hyperthyroidism, or high thyroid hormone levels.

• Kidney or liver function problems. These patients are started with a low dose.

• Skin condition called psoriasis.

• Untreated pheochromocytoma, which is a tumor of the adrenal gland.

• Metabolic acidosis like diabetic ketoacidosis.

What are the side effects of Nebivolol?

Heart- Slow heart rate, heart failure, low blood pressure .
Gastrointestinal- Diarrhea, nausea, abdominal pain,constipation.
Central Nervous System- Headache, dizziness, sleeplessness, weakness, tingling.
Respiratory- Wheezing, cough, nasopharyngitis (inflammation of nose and throat).
Skin- Rash.
Metabolic- Increased level of cholesterol, and uric acid in the blood.
Others: fatigue, peripheral edema, joint pain, rash

What are the other precautions for Nebivolol?

Avoid excess dosage.
Nebivolol may cause dizziness, do not drive a car or operate machinery while taking this medication.

What are the Drug Interactions of Nebivolol?

Nebivolol should be avoided with:
• Other beta blockers due to additive effects.
• Other drugs with depressant effects on the heart including calcium channel blockers like amlodipine, verapamil and diltiazem, heart failure drugs digoxin or digitoxin, and drugs that normalize heart rhythm like quinidine, disopyramide, flecainide, and mexiletine. Combination with some of these drugs may be necessary in cases that cannot be controlled with a single drug.
• Antidiabetic drugs since nebivolol can block the signs and of low blood sugar levels.
• Drugs that inhibit CYP2D6 enzyme like paroxetine, fluoxetine and thioridazine, which can increase nebivolol level in the blood resulting in reduced heart rate.
• Drugs used in the treatment of asthma due to opposite effects on the bronchi.
• Non-steroidal anti-inflammatory drugs like ibuprofen and diclofenac which may block the action of nebivolol on blood pressure.
• Other drugs which reduce blood pressure due to additive effect.
• Antipsychotics like phenothiazines, barbiturates and tricyclic antidepressants due to excessive reduction in heart rate.

What are the storage conditions for Nebivolol?

Oral: Store it at room temperature (20-25°C) and in an airtight container.Protect from excess heat and moisture. Keep out of reach of children.

Learn more about Nebivolol : Interaction with Foods, Herbs, Alcohol and Caffeine

Q: Is Nebivolol safe to use in elderly patients?

A: Nebivolol can be given to patients who are 65 years of age or older. In this patient group, the doctor would start with the lowest dose and gradually increase the dosage. In patients who are 75 years or older, it is important to monitor their blood pressure while taking this medication ().

Q: Does Nebivolol increase cholesterol levels?

A: Nebivolol is less likely to affect cholesterol levels. Consult a healthcare professional about eating healthier and exercising if you experience any increase in cholesterol levels ().

Q: Is it safe to use Nebivolol in patients with kidney disease?

A: Nebivolol use in patients with moderate renal impairment was not associated with major safety concerns. It is safe and effective in treating blood pressure in mild or moderate renal impairment patients ().

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