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Misoprostol - Indications, Dosage, Side Effects and Precautions

Last Updated on Nov 24, 2010
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Information about Misoprostol

Generic Name : Misoprostol
Pronunciation : MYE-soe-PROST-ol
Latest prescription information about Misoprostol. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y53.0 | Therapeutic Classification : Antiulcers

Trade Names/Brand Names of Misoprostol


Why is Misoprostol Prescribed? (Indications)

This medication is a synthetic prostaglandin; prescribed for ulcer, labor induction, induced abortion, miscarriage, postpartum hemorrhage (blood loss during birth) and other gynecological uses. It reduces the acid secretion in stomach.


When should Misoprostol not be taken? (Contraindications)

Contraindicated in pregnant women, and known hypersensitivity.

What is the dosage of Misoprostol?

Adult: PO- The recommended dose is 200 mcg four times daily with food. If this dose cannot be tolerated, a dose of 100 mcg can be used.

How should Misoprostol be taken?

It comes, as a tablet to take by mouth, with food.

What are the warnings and precautions for Misoprostol?

• It may cause abortion, premature birth, or birth defects, uterine rupture; it should not be used during pregnancy.

Caution should be exercised in patients with history of low blood pressure, which may lead to severe complications e.g. brain or heart disease, inflammatory bowel disease and kidney impairment, elderly, children.

It may lead to dehydration, drink adequate water.

What are the side effects of Misoprostol?

  Most Common: Spotting, cramps, heavy periods, Excessive Urination, menstrual disorder, painful menstruation and postmenopausal vaginal bleeding and breast pain.
  Body as a whole : Aches/pains, weakness, fatigue, fever, chills and weight changes.
  Skin : Rash, inflammation, hair loss and pallor (paleness).
  Eye and ENT: Abnormal taste, abnormal vision, inflammation of eye, deafness, ringing and pain in the ear.
  Respiratory : Upper respiratory tract infection, difficulty in breathing, pneumonia and nose bleed.
  Heart: Chest pain, edema, excessive sweating, low/high blood pressure, abnormal heart rate, inflammation of blood vessels, fainting, heart attack and blood clot events.
  Gastrointestinal: Nausea, GI bleeding, GI inflammation/infection, rectal disorder, vomiting, diarrhea, abnormal liver function, reflux and difficulty in swallowing.
  Hypersensitivity : Anaphylaxis.
  Metabolic : Excretion of glucose into the urine, gout and increased nitrogen level.
  Genitourinary : Excessive urination, painful urination, blood in urine and urinary tract infection.
  Central Nervous System : Headache, anxiety, changes in appetite, depression, drowsiness, dizziness, thirst, impotence, loss of libido, increased sweating, nerve damage, mental disorder and confusion.
  Musculoskeletal : Joint/muscle pain, muscle cramps, stiffness and back pain.
  Blood : Anemia, decrease in platelets, bruising and increase in ESR level.

What are the other precautions for Misoprostol?

It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

What are the storage conditions for Misoprostol?

Oral: Store it at room temperature or below 25C (77F) in an airtight container.

Last Updated : May 2018

Misoprostol: Drug to Induce Labor/Cause Abortion and Treat Stomach Ulcers

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daynighthealthcare, India

Cytotec contains Misoprostol as active ingredient which is help to terminate unwanted pregnancy up to 8 weeks with safe home abortion method. With this home abortion pill there is no required to for clinical administration and along with it will perform safe abortion without surgical instrument. Cytotec is also used to stop stomach ulcers. http://goo.gl/NPq1wM

babloo, India

if a pregnant lady take for avoid pregnancy, what is the other side effect after taking the medicine.

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