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Mifepristone - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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Information about Mifepristone

Generic Name : Mifepristone
Pronunciation : MIF-eh-pri-stone
Latest prescription information about Mifepristone. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Antiprogesterone

Trade Names/Brand Names of Mifepristone

India : 

International : 


Why is Mifepristone Prescribed? (Indications)

This medication is a synthetic steroid, used alone or together with another medication, to end an early pregnancy (within 7 weeks of the start of a woman's last menstrual period). It blocks the hormone needed for pregnancy to continue. It is also indicated for high blood sugar levels (hyperglycemia) in adults with endogenous Cushing’s syndrome.  

When should Mifepristone not be taken? (Contraindications)

Contraindicated in patients with confirmed or suspected fertilized egg has implanted outside the uterus, chronic adrenal failure, concurrent long-term corticosteroid therapy, history of allergy to mifepristone, misoprostol or other prostaglandin, bleeding disorders, liver or kidney impairment; pregnancy and lactation; IUD in place; undiagnosed uterus mass.

What is the dosage of Mifepristone?

Oral- Termination of pregnancy (49 days or less duration)- Adult: 600 mg as a single dose followed 2 days later by 400 mcg of misoprostol as single dose.

How should Mifepristone be taken?

This medication available in the form of tablet to take by mouth with or without food, only under healthcare provider’s supervision. First time 2 tablets, if it doesn't work.

What are the warnings and precautions for Mifepristone?

• Do not use this if your pregnancy is outside the womb (ectopic pregnancy). It will not cause an abortion in this case.

• It may cause dizziness. Do not drives, operate machinery, or do anything while taking this medication.

• It should be used with caution in patients with kidney, heart, lung, liver, adrenal disease. Patients with diabetes, high blood pressure and porphyria should also inform their doctor about their illness prior to taking this medication.

What are the side effects of Mifepristone?

  Genitourinary: Excessive vaginal bleeding, uterus infections, uterus bleeding, urinary tract infection.
  Gastrointestinal: Diarrhea, nausea, vomiting, stomach cramps.
  Central Nervous System: Dizziness, headache, anxiety, fatigue, unusual tiredness or weakness.
  Metabolic: Swelling in the extremities and decreased appetite.
  Musculoskeletal: Joint pain.
  Miscellaneous: Back pain, fever.

What are the other precautions for Mifepristone?

Avoid smoking, alcohol consumption.

What are the storage conditions for Mifepristone?

Normally handled and stored by healthcare providers.

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estellaclayes, United States

Hello friend! This is me, Estella, senior women health advisor. I want to share about Mifeprex[mifepristone] as my most of client had successfully aborted using Mifepristone. As I worked as a researcher and advisor since a decade I found this FDA approved the drug is proved very satisfactory for women who have an unwanted pregnancy. I appreciate the information shared by The Medindia and also the author Ms. Anushta above on such a helpful medication and process.

marlene765, South Africa

Am so happy, i never believe i will be this happy again in life, I was working as an air-hoster [ cabby crew ] for 5 years but last year i loose my job because of this deadly disease called Hepatitis B (HbsAg), I never felt sick or have any symptom, till all workers were ask to bring their doctor report, that was how i got tested and i found out that am HbsAg positive that make me loose my job, because it was consider as an STD and is incurable disease, i was so depress was thinking of committing suicide, till i explain to a friend of mine, who always said to me a problem share is a problem solved, that was how she directed me to this clinic contacted them and i get medication from them and i got cured for real, I just went back to my work and they also carry out the test to be real sure and i was negative.


Nice post. Mifepristone is best medicine used to terminate unwanted pregnancy up to 7 weeks.


Hello friends!!!! my name is Lisa Lebel am from USA , i want to share this great and wonderful testimony to the general public on how i got cured from my sickness called [HEPATITIS B] by DR OJEMEN healing herbal medicine , I have been suffering from (HEPATITIS B) for good 6 years now and I was almost going to the end of my life due to the constant pain, especially in my LIVER . all I have in my mind is let me just give up because life was no longer intestine to me any more but I just pray to God every day to accept my soul when ever I die, luckily to me , my kid sister ran to me that she found a doctor in the internet who can cure (HEPATITIS B, HERPES,CANCER, and HIV/AIDS ) she helped me out on everything, the great Dr OJEMEN only ask for my Details and some items , so that he can prepare a Herbal medicine for me and send it to me in my country , which he did.. so after two days of getting the medicine and taking it as prescribe to me from him , I started getting more stronger my blood started flowing normally , i started experiencing changes all over my Body as the great DR OJEMEN assured me that i should go for medical check up that i have been cured, so after some time i went to my doctor to confirmed if i have be finally healed , behold it was TRUE and i was very Happy ,so if you have HERPES , HEPATITIS B ,CANCER , HIV/AIDS or any kind of sickness YOU HAVE , you can contact him and also he do cast love spell , and any kind of spell you can think off or any illness get cured, i advice you all to contact him on Via mail at (drojemenspellhome@hotmail.com)or call him 2349052116214. Good luck .

SNTalukdar, India

I m 40 days pregnant and wan to use Mifepriston, will it work?

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