Information about Mifepristone
Generic Name : Mifepristone
Pronunciation : MIF-eh-pri-stone
Latest prescription information about Mifepristone. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Antiprogesterone
Trade Names/Brand Names of Mifepristone
Why is Mifepristone Prescribed? (Indications)
This medication is a synthetic steroid, used alone or together with another medication, to end an early pregnancy (within 7 weeks of the start of a woman's last menstrual period). It blocks the hormone needed for pregnancy to continue. It is also indicated for high blood sugar levels (hyperglycemia) in adults with endogenous Cushing’s syndrome.
When should Mifepristone not be taken? (Contraindications)
Contraindicated in patients with confirmed or suspected fertilized egg has implanted outside the uterus, chronic adrenal failure, concurrent long-term corticosteroid therapy, history of allergy to mifepristone, misoprostol or other prostaglandin, bleeding disorders, liver or kidney impairment; pregnancy and lactation; IUD in place; undiagnosed uterus mass.
What is the dosage of Mifepristone?
Oral- Termination of pregnancy (49 days or less duration)- Adult: 600 mg as a single dose followed 2 days later by 400 mcg of misoprostol as single dose.
How should Mifepristone be taken?
This medication available in the form of tablet to take by mouth with or without food, only under healthcare provider’s supervision. First time 2 tablets, if it doesn't work.
What are the warnings and precautions for Mifepristone?
• Do not use this if your pregnancy is outside the womb (ectopic pregnancy). It will not cause an abortion in this case.
• It may cause dizziness. Do not drives, operate machinery, or do anything while taking this medication.
• It should be used with caution in patients with kidney, heart, lung, liver, adrenal disease. Patients with diabetes, high blood pressure and porphyria should also inform their doctor about their illness prior to taking this medication.
What are the side effects of Mifepristone?
• Genitourinary: Excessive vaginal bleeding, uterus infections, uterus bleeding, urinary tract infection.
• Gastrointestinal: Diarrhea, nausea, vomiting, stomach cramps.
• Central Nervous System: Dizziness, headache, anxiety, fatigue, unusual tiredness or weakness.
• Metabolic: Swelling in the extremities and decreased appetite.
• Musculoskeletal: Joint pain.
• Miscellaneous: Back pain, fever.
What are the other precautions for Mifepristone?
Avoid smoking, alcohol consumption.
What are the storage conditions for Mifepristone?
Normally handled and stored by healthcare providers.