Email Print This Page Comment bookmark
Font : A-A+

General Information on Lepirudin

Generic Name : Lepirudin

Pronunciation : le-PEER-u-din

Latest prescription information about Lepirudin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y44.2 | Therapeutic Classification : Anticoagulants / Antithrombotics

Trade Names/Brand Names of Lepirudin

International- Refludan.

Why is Lepirudin Prescribed? (Indications)

This medication is an anticoagulant, prescribed for heparin-induced thrombocytopenia (HIT). It blocks thrombin activity that helps to prevent the formation of blood clots.

When should Lepirudin not to be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Lepirudin?

Adult: IV- 0.4 mg/kg body weight (up to 110kg) slowly intravenously (eg, over 15 to 20seconds) as a bolus dose.
Followed by 0.15 mg/kg body weight (up to 110kg)/hour as a continuous intravenous infusion for 2 to 10 days or longer if clinically needed.

How should Lepirudin be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Lepirudin?

Caution should be exercised in patients with history of heart infection, high blood pressure, stomach ulcers, liver or kidney problems, head injury, stroke, any allergy, bleeding problems, stomach/intestinal problems, elderly, children, during pregnancy and breastfeeding.

Monitor blood counts, blood pressure while taking this medication.

What are the side effects of Lepirudin?

  Heart: Heart failure.
  Skin: Bleeding in injection site, wounds and allergic skin reactions.
  Eye and ENT: Nosebleed.
  Gastrointestinal: Gastrointestinal and rectal bleeding.
  Genitourinary: Abnormal kidney function, blood in urine and vaginal bleeding.
  Blood: Anemia and sepsis.
  Liver: Abnormal liver function.
  Respiratory: Pneumonia.
  Miscellaneous: Fever and infection.

What are the other precautions for Lepirudin?

Avoid alcohol consumption.

What are the storage conditions for Lepirudin?

Store it at controlled room temperature (2 to 25C).

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions
Buy Medicines (Drug) at Concessional Price from India

Drugs A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Drugs Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Stay Connected

  • Available on the Android Market
  • Available on the App Store