This medication is a sulfonylurea antidiabetic agent, prescribed for type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood), particularly in people whose diabetes cannot be controlled by diet alone. It increases the amount of insulin secretion and thus regulates the sugar level in the blood.
Contraindicated in patients with hypersensitivity, Type 1 diabetes, ketoacidosis, severe kidney or liver impairment, pregnancy and breastfeeding.
PO: Initial-2.5 to 5 mg/day as a single dose may increase slowly. Doses greater than 15 mg may be given in 2 divided doses. Max: 40 mg/day.
Extended-release: Should be taken with food. (Swallow whole, do not chew/ crush/ divide.)
Immediate-release: Should be taken on an empty stomach. (Take ½ hour before meals.)
Caution should be exercised in patients with history of liver, blood disorder.
Do not drink alcohol while you are taking this medication. It may increase the risk of low blood sugar.
It may increase the risk of death from heart disease, thyroid problem, moderate liver or kidney failure.
Monitor blood glucose concentration.
Low blood sugar.
Heart: Increased risk of death due to heart problems.
Central Nervous System: Dizziness and vertigo.
Skin: Allergic skin reactions, inflammation of skin, itching, redness, hives, eruptions and photosensitivity.
Eye and ENT: Tinnitus.
Gastrointestinal: GI disturbances (eg, nausea, loss of appetite, heartburn) and diarrhea.
Genitourinary: Mild urinary frequency, elevated Blood, Urea, Nitrogen and creatinine levels.
Liver: Jaundice and elevated LFT (liver function test) results.
Blood: Decrease in white blood cells, platelets, hemoglobin.
Miscellaneous: Disulfiram like reaction (symptoms like uneasiness, vomiting, mental confusion, chest pain, headache etc on taking alcohol while on the medication), weakness, tingling, fatigue and uneasiness.
Proper diet, regular exercise needed. Do not change the dose of your medicine without checking with your doctor.
Store it at room temperature and away from excess heat and moisture. Keep in an airtight container and keep away from children.
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