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General Information on Glipizide

Generic Name : Glipizide

Pronunciation : GLIP-i-zide

Latest prescription information about Glipizide. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y42.3 | Therapeutic Classification : Antidiabetics

Why is Glipizide Prescribed? (Indications)

This medication is a sulfonylurea antidiabetic agent, prescribed for type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood), particularly in people whose diabetes cannot be controlled by diet alone. It increases the amount of insulin secretion and thus regulates the sugar level in the blood. 

When should Glipizide not to be taken? (Contraindications)

Contraindicated in patients with hypersensitivity, Type 1 diabetes, ketoacidosis, severe kidney or liver impairment, pregnancy and breastfeeding.

What is the dosage of Glipizide?

PO: Initial-2.5 to 5 mg/day as a single dose may increase slowly. Doses greater than 15 mg may be given in 2 divided doses. Max: 40 mg/day.

How should Glipizide be taken?

Extended-release: Should be taken with food. (Swallow whole, do not chew/ crush/ divide.)
Immediate-release: Should be taken on an empty stomach. (Take ½ hour before meals.)

What are the warnings and precautions for Glipizide?

• Caution should be exercised in patients with history of liver, blood disorder.

• Do not drink alcohol while you are taking this medication. It may increase the risk of low blood sugar.

• It may increase the risk of death from heart disease, thyroid problem, moderate liver or kidney failure.

• Monitor blood glucose concentration.

What are the side effects of Glipizide?

•  Metabolic: Low blood sugar.
•  Heart: Increased risk of death due to heart problems.
•  Central Nervous System: Dizziness and vertigo.
•  Skin: Allergic skin reactions, inflammation of skin, itching, redness, hives, eruptions and photosensitivity.
•  Eye and ENT: Tinnitus.
•  Gastrointestinal: GI disturbances (eg, nausea, loss of appetite, heartburn) and diarrhea.
•  Genitourinary: Mild urinary frequency, elevated Blood, Urea, Nitrogen and creatinine levels.
•  Liver: Jaundice and elevated LFT (liver function test) results.
•  Blood: Decrease in white blood cells, platelets, hemoglobin.
•  Miscellaneous: Disulfiram – like reaction (symptoms like uneasiness, vomiting, mental confusion, chest pain, headache etc on taking alcohol while on the medication), weakness, tingling, fatigue and uneasiness.

What are the other precautions for Glipizide?

Proper diet, regular exercise needed. Do not change the dose of your medicine without checking with your doctor.

What are the storage conditions for Glipizide?

Store it at room temperature and away from excess heat and moisture. Keep in an airtight container and keep away from children.

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edwardhoward, India

Glipizide is an oral medication used to lower blood glucose levels in type 2 diabetes [non-insulin-dependent diabetes] patients. It belongs to a class of drugs called sulfonylureas, which work by stimulating the pancreas to produce more insulin.

KMShah, India

How to overcome side effects? i.e. loss of appetite/weight loss etc

Doosriradha, India

JAYA JAYA SHRI KRUSHNA! I just chanced upon this medicine Glipizide for Diabetes Type-2. The information you have given here are complete and very helpful. I wonder why I was prescribed Gemer1. That is Metformin. Now, I want to know if Glipizide would be a better medicine for me.

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