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General Information on Flumazenil

Generic Name : Flumazenil

Pronunciation : flew-MAY-zee-nill

Latest prescription information about Flumazenil. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y57.2 | Therapeutic Classification : Antidotes

Trade Names/Brand Names of Flumazenil

International- Anexate,Lanexat, Mazicon, Romazicon.

Why is Flumazenil Prescribed? (Indications)

This medication is a benzodiazepine antagonist, prescribed for reversing drowsiness, sedation and other effects caused by benzodiazepine. It is also used for hepatic encephalopathy (confusion, altered level of consciousness and coma as a result of liver failure).  

When should Flumazenil not to be taken? (Contraindications)

Contraindicated in patients with hypersensitivity, who have been given benzodiazepine for control of a potentially life-threatening condition, who have experienced with serious side effects due to overdose of depression medications.

What is the dosage of Flumazenil?

Adult: IV- The recommended dose is 200 μg every 1�2 minutes until the effect is seen, to a maximum of 3 mg per hour.

How should Flumazenil be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Flumazenil?

Caution should be exercised in patients with history of seizures, panic attacks, alcohol or drug dependency, breathing disorders, heart disease, liver disease, head injury, allergies, elderly, children, during pregnancy and breastfeeding.

Patient may develop with increased risk of epilepsy, respiratory depression, if it so consult with your doctor.

It may cause lightheadedness, dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

What are the side effects of Flumazenil?

  Most frequent: Dizziness, injection site pain, increased sweating, headache and abnormal or blurred vision.
  Body as a Whole: Fatigue, weakness, uneasiness and injection site pain.
  Heart: Dilation of blood vessels, flushing, palpitations and hot flushes.
  Gastrointestinal: Nausea, vomiting and dry mouth.
  Central Nervous System: Agitation, anxiety, nervousness, tremor, sleeplessness, and emotional lability.
  Respiratory: Difficulty in breathing.

What are the other precautions for Flumazenil?

Avoid alcohol consumption.

What are the storage conditions for Flumazenil?

Store it at controlled room temperature (25°C).

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