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General Information on Estramustine

Generic Name : Estramustine

Pronunciation : ESS-truh-muss-TEEN

Latest prescription information about Estramustine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Trade Names/Brand Names of Estramustine

India : 

International : 

Emcyt

Why is Estramustine Prescribed? (Indications)

This medication is antimicrotubule agent, prescribed for the partial treatment of prostate cancer.  It stops the growth and spread of cancer cells.

When should Estramustine not to be taken? (Contraindications)

Contraindicated in patients with obstruction in blood circulation, and hypersensitivity.

What is the dosage of Estramustine?

PO- The recommended daily dose is 14 mg per kg of body weight in divided doses.

How should Estramustine be taken?

It comes as a capsule to take by mouth, on an empty stomach.

What are the warnings and precautions for Estramustine?

Caution should be exercised in patients with history of blood clot, diabetes, high blood pressure, stroke, congestive heart disease, migraines, seizures, liver or kidney disease, parathyroid disorder, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may affect the metabolism of calcium and phosphorus.

Monitor liver function and bilirubin level regularly while taking this medication.

What are the side effects of Estramustine?

   Heart : Heart arrest, stroke, heart attack, inflammation of blood vessels, blood clot in lungs, heart failure and fluid retention.
   Respiratory : Difficulty in breathing, leg cramps, upper respiratory discharge and hoarseness.
   Gastrointestinal : Nausea, diarrhea, gastrointestinal upset, loss of appetite, flatulence, vomiting, gastrointestinal bleeding, burning throat and thirst.
   Skin : Rash, itching, dry skin, pigmentation, bruising, flushing, night sweats, fingertip-peeling skin and thinning of hair.
   Genitourinary : Breast tenderness and enlargement.
   Miscellaneous : Lethargy, depression, emotional lability, sleeplessness, headache, anxiety, hot flashes, eye pain, tearing and ringing in the ear.
   Blood : Decrease in white blood cells and platelets.

What are the other precautions for Estramustine?

Avoid excess dosage.

What are the storage conditions for Estramustine?

Store it in refrigerator (2 to 8C).


Schedule : H

Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.

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