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Estradiol - Indications, Dosage, Side Effects and Precautions

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Information about Estradiol

Generic Name : Estradiol
Up-to-date prescription details regarding Estradiol are provided here.

Pronunciation : ES-tra-DYE-ol

Learn the correct pronunciation of the Estradiol, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y42.5 Therapeutic Classification : Hormones

Trade Names/Brand Names of Estradiol

India :

International :


Divigel Gel, E 2 Vaginal Tab Tab, E2 Gel Gel, Estraderm Mx Patch, Estrofem Tab, Ets Patch Patch, Evalon Crm Cream, Evalon Tab, Oestrogel Gel, Progynon Depot Inj, Progynova Tab, Sandrena Gel

Why is Estradiol Prescribed? (Indications)

This medication is a sex hormone, prescribed for treating conditions due to menopause, treating vulval or vaginal atrophy, prostate cancer, and preventing osteoporosis (brittle bones). It is also used for estrogen replacement therapy after failure of the ovaries and to relieve the symptoms of breast cancer.

When should Estradiol not be taken? (Contraindications)

Contraindicated in patients with hypersensitivity; undiagnosed vaginal bleeding; clot in blood vessels; breast cancer, estrogen-dependent tumor; disorders of certain enzymes; pregnancy.

What is the dosage of Estradiol?

Estradiol dosage varies according to indication and route of administration.

How should Estradiol be taken?

It may be administered orally, as an intramuscular injection or applied to the skin or mucous membranes.

What are the warnings and precautions for Estradiol?

•Conditions that become more severe with estrogen include fluid retention; increase in calcium level, poor blood flow to the brain, coronary artery disease, gall bladder diseases; lipid effects; familial defects of lipoprotein metabolism.

May increase blood pressure, risk of blood clot in the vein, breast cancer, benign tumor of the liver, endometrial cancer, dementia and size of preexisting uterine fibroid.

• Dosage should be reduced in liver problem and during breastfeeding.

It should not be used in children.

What are the side effects of Estradiol?

Central Nervous System- Headache, dizziness, sleeplessness, depression, anxiety, nervousness, migraine.
Gastrointestinal- Abdominal distension, abdominal pain, flatulence, nausea, constipation, upset stomach , diarrhea, bleeding, toothache, tooth disorder.
Skin- Rash, itching, inflammation of the skin, skin scar.
Heart- Temporary loss of consciousness and posture, vein inflammation.
Genitourinary- Abnormal bleeding during menstrual cycles, breast pain, breast tenderness, vaginal bleeding, vaginal discomfort, blood in urine, urinary incontinence.

What are the other precautions for Estradiol?

Monitor blood sugar level regularly, in case if you have diabetes.

What are the storage conditions for Estradiol?

Store it at room temperature.

Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.
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