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General Information on Dexmedetomidine

Generic Name : Dexmedetomidine

Pronunciation : dex-MED-e-TO-mi-dine HYE-droe-KLOR-ide

Latest prescription information about Dexmedetomidine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y47.8 | Therapeutic Classification : Sedative-hypnotic Drugs

Trade Names/Brand Names of Dexmedetomidine

Why is Dexmedetomidine Prescribed? (Indications)

This medication is a sedative, prescribed for intensive care unit sedation and procedural sedation. 

When should Dexmedetomidine not to be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Dexmedetomidine?

Dosage is based on patient’s condition and response to the medication.
IV: The recommended loading dose is 1mcg/kg over 10 minutes. Maintenance: 0.6mcg to 1mcg/kg/hr.

How should Dexmedetomidine be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Dexmedetomidine?

• A skilled person who has enough knowledge in handling intensive care unit patients should administer this medication.

• Patient may develop with low heart rate, high blood pressure, sinus arrest, if it so either decrease the dosage or stop the medication.

• Caution should be exercised in patients with history of heart diseases, decrease in blood volume, diabetes, chronic high blood pressure, elderly, during pregnancy and lactation.

What are the side effects of Dexmedetomidine?

•  Most Common: Low blood pressure, slow heart rate and dry mouth.
•  Body as a Whole : Fever, decreased blood volume, light anesthesia, pain and rigors.
•  Heart: Blood pressure fluctuation, high/low blood pressure, heart attack, abnormal heart rhythm, fast/slow heart rate and dilation of blood vessels.
•  Central Nervous System : Dizziness, headache, nerve pain/inflammation, speech disorder, convulsion, anxiety, agitation, confusion, hallucination and illusion.
•  Gastrointestinal : Abdominal pain, diarrhea, vomiting, nausea and constipation.
•  Liver: Increased level of liver enzymes and liver damage.
•  Metabolic: Excess level of acid in blood, increased potassium level in blood and decrease/increase in sugar level.
•  Blood: Anemia, easy bruising and bleeding.
•  Genitourinary: Blood urea nitrogen increased and decreased urination.
•  Respiratory : Asthma, shortness/poor breathing and lung obstruction.
•  Skin : Increased sweating.
•  Eye: Abnormal eye sensation and abnormal vision.

What are the other precautions for Dexmedetomidine?

Take full course of treatment.

What are the storage conditions for Dexmedetomidine?

Store it at controlled room temperature (25°C), and in an airtight container.

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vijispu, India

Can dexem infusion be used for postoperative patients with alcohol withdrawal ?

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