This medication is a chemotherapeutic agent, prescribed for acute myeloid leukemia and acute lymphocytic leukemia. This medication slows the growth and spread of cancer cells in the body.
Contraindicated in patients with heart disease and hypersensitivity.
IV- Adult- The recommended dose is 60 – 75mg/m2/day BSA (body surface area), every 3 weeks.
It comes as a solution for injection to be administered by a healthcare provider into the vein.
• Caution should be exercised in patients with heart, kidney or liver disease, bone marrow depression, gout, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
• Patient may develop with increased risk of heart disease (myocardial toxicity), bone marrow depression and secondary malignancy (cancer); if it is so consult with your doctor immediately.
• It may reduce platelet counts, which leads to bleeding; avoid injury or bruising.
• Monitor complete blood cell counts, heart, liver and kidney functions regularly while taking this medication.
• Avoid contact with people with infections.
• Skin :
Rash, skin inflammation and hives.
• Gastrointestinal : Nausea, vomiting, diarrhea and abdominal pain.
• Local : Cell death and painful induration.
• Miscellaneous : Fever, chills and rarely allergic reactions.
Avoid drinking alcoholic beverages.
Avoid excess dosage.
Injection: Store it in refrigerator (2-8°C). Do not freeze.
Powder for injection: Store it at controlled room temperature (15-25°C).
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